97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
久久亚洲aⅴ永久无码精品,国产在线观看AV一区二区,日韩在线观看中文
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-ERCC6L/APC Conjugated antibody (bs-6380R-APC)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-6380R-APC
英文名稱 Rabbit Anti-ERCC6L/APC Conjugated antibody
中文名稱 APC標記的發育相關蛋白ERCC6L/乙醇致畸因子抗體
別    名 ATP dependent helicase ERCC6 like; DNA excision repair protein ERCC 6 like; ERCC 6L; ERCC6L; Excision repair cross complementing rodent repair deficiency complementation group 6 like; Excision repair protein ERCC6 like; FLJ20105; MGC131695; PICH; Plk1 interacting checkpoint helicase; SNF2/RAD54 family protein; Tumor antigen BJ HCC 15; ERC6L_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  發育生物學  細胞周期蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Sheep, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 141kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ERCC6L
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
ERCC6L belongs to the SNF2 ATPase family and acts as an essential component of the spindle assembly checkpoint. It contributes to the mitotic checkpoint by recruiting MAD2 to kinetochores and monitoring tension on centromeric chromatin. It acts as a tension sensor that associates with catenated DNA which is stretched under tension until it is resolved during anaphase. ERCC6L may also play a role in the teratogenic action of alcohol.

Function:
DNA helicase that acts as an essential component of the spindle assembly checkpoint. Contributes to the mitotic checkpoint by recruiting MAD2 to kinetochores and monitoring tension on centromeric chromatin. Acts as a tension sensor that associates with catenated DNA which is stretched under tension until it is resolved during anaphase.

Subunit:
Interacts with PLK1, which phosphorylates it. Both proteins are mutually dependent on each other for correct subcellular localization.

Subcellular Location:
Chromosome, centromere. Chromosome, centromere, kinetochore. Note=Localizes to kinetochores, inner centromeres and thin threads connecting separating chromosomes even during anaphase. In prometaphase cells, it mostly concentrates in between kinetochores. In metaphase, it localizes to numerous thin threads that stretch between sister kinetochores of the aligned chromosomes and are composed of catenated centromeric DNA. Evolution from inner centromeres to thin threads takes place in response to tension. Resolution of thin threads requires topoisomerase 2-alpha (TOP2A) after anaphase onset.

Post-translational modifications:
Phosphorylation by PLK1 prevents the association with chromosome arms and restricts its localization to the kinetochore-centromere region.

Similarity:
Belongs to the SNF2/RAD54 helicase family.
Contains 1 helicase ATP-binding domain.
Contains 1 helicase C-terminal domain.
Contains 2 TPR repeats.

Database links:

Entrez Gene: 54821 Human

Omim: 300687 Human

SwissProt: Q2NKX8 Human

Unigene: 47558 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 在线国产精品一区 | 久草在线资源总站 | 国产69精品久久99不卡免费版 | 国偷自产一区二区视频 | 四虎国产精品成人 | 深夜免费观看视频 | 国产成人无码午夜视频在线观看 | www.av在线免费观看 | 亚洲一区二区在线免费视频 | 亚洲久本草在线中文字幕 | 亚洲亚色 | 91久视频| 久久不卡视频 | 秋霞无码一区二区视频在线观看 | 永久免费看毛片 | 日本一区二区三区免费软件 | 久久国产午夜精品理论片推荐 | 亚洲欧洲自拍拍偷无码 | 四川少妇搡BBW搡BBBB | 久久不卡免费视频 | 人人澡人人曰人人摸看 | 久久精品国产99久久久 | 91综合网人人 | yy6080午夜我不卡 | 国产在线午夜卡精品影院 | 69堂免费视频 | 久草精品在线观看 | 国产成人综合激情视频在线观看 | 国产欧美一区二区三区免费 | 中国XXXXXL19免费视频 | 懂色av网 | 亚洲影院久久精品 | 日本a级在线播放 | 一区二区三区四区视频免费观看 | 午夜av成人| 成人综合婷婷国产精品久久蜜臀 | 色欲av久久无码影院色戒 | 扒开粉嫩的小缝隙喷白浆 | 00271最新网站地址一 | 亚洲成人免费看 | 日本孕妇潮喷高潮视频 |