97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
av视频在线观看,9久精品,国产老女人乱淫免费
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-STK18/BF488 Conjugated antibody (bs-6393R-BF488)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-6393R-BF488
英文名稱 Rabbit Anti-STK18/BF488 Conjugated antibody
中文名稱 BF488標記的絲氨酸/蘇氨酸蛋白激酶18
別    名 PLK 4; PLK-4; PLK4; PLK4_HUMAN; Polo like Kinase 4; Polo-like kinase 4; Protein serine/threonine kinase; SAK; Serine/Threonine Kinase 18; Serine/threonine kinase; Serine/threonine protein kinase 18; Serine/threonine protein kinase PLK4; Serine/threonine protein kinase Sak; Serine/threonine-protein kinase 18; Serine/threonine-protein kinase PLK4; Serine/threonine-protein kinase SAK; Snk Akin Kinase; STK 18; STK18.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  免疫學  信號轉導  細胞周期蛋白  激酶和磷酸酶  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 108kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PLK4/STK18
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Serine/threonine-protein kinase that plays a central role in centriole duplication. Able to trigger procentriole formation on the surface of the parental centriole cylinder, leading to the recruitment of centriole biogenesis proteins such as SASS6, CENPJ/CPAP, CP110, CEP135 and gamma-tubulin. When overexpressed, it is able to induce centrosome amplification through the simultaneous generation of multiple procentrioles adjoining each parental centriole during S phase. Its central role in centriole replication suggests a posible role in tumorigenesis, centrosome aberrations being frequently observed in tumors. Also involved in trophoblast differentiation by phosphorylating HAND1, leading to disrupt the interaction between HAND1 and MDFIC and activate HAND1. Phosphorylates CDC25C and CHEK2/CHK2.

Function:
Serine/threonine-protein kinase that plays a central role in centriole duplication. Able to trigger procentriole formation on the surface of the parental centriole cylinder, leading to the recruitment of centriole biogenesis proteins such as SASS6, CENPJ/CPAP, CP110, CEP135 and gamma-tubulin. When overexpressed, it is able to induce centrosome amplification through the simultaneous generation of multiple procentrioles adjoining each parental centriole during S phase. Its central role in centriole replication suggests a posible role in tumorigenesis, centrosome aberrations being frequently observed in tumors. Also involved in trophoblast differentiation by phosphorylating HAND1, leading to disrupt the interaction between HAND1 and MDFIC and activate HAND1. Phosphorylates CDC25C and CHEK2.

Subunit:
Homodimer. Interacts with CEP152 (via N-terminus).

Subcellular Location:
Cytoplasm, cytoskeleton, centrosome, centriole. Nucleus, nucleolus.

Post-translational modifications:
Ubiquitinated; leading to its degradation by the proteasome.
Tyrosine-phosphorylated by TEC.

Similarity:
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.

Database links:

Entrez Gene: 10733 Human

Entrez Gene: 20873 Mouse

Entrez Gene: 310344 Rat

SwissProt: O00444 Human

SwissProt: Q64702 Mouse

SwissProt: B2GUY1 Rat

Unigene: 172052 Human

Unigene: 3794 Mouse

Unigene: 14848 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 东京复仇者第三季天竺篇在线观看 | 好男人社区神马影视www | 欧美国产综合在线 | 色妞AV永久一区二区国产AV | 青春草91| 欧美网站大全在线观看 | 性色AV一区二区三区无码 | 超碰在线人人艹 | 免费视频18上在线观看 | 最新大地资源网在线观看免费 | 国产欧美精品在线观看 | 亚洲精品久久久中文字幕 | yp在线观看视频网址入口 | 99久久综合国产精品二区国产 | 男男做爰猛烈高潮在线观看 | 久久日韩精品一区鲁大师 | 一级级黄 | 亚洲黄色在线免费观看 | 久久精品人妻无码一区二区三区 | 性刺激的大陆三级视频 | 国产欧美日产久久 | 色欲狠狠躁天天躁无码中文字幕 | 国产成在线观看免费视频成本人 | 极品束缚调教一区二区网站 | 国产精品嫩草99av在线 | 一本久久综合亚洲鲁鲁五月天 | 日韩精品一区二区三区四区视频 | 精品久久久久久久人人人人传媒 | 年轻富婆私密推油到高潮 | 久久躁狠狠躁夜夜AV | 91精品国产自产在线观看自播 | 日韩人妻精品一区二区三区视频 | 扒开粉嫩的小缝隙喷白浆 | 国产视频91在线 | aⅴ黄色 | 精品久久久久免费极品大片 | 四虎永久在线精品视频 | 美丽姑娘免费高清观看 | 任你操精品视频 | 青青草欧美 | gogo大胆无码免费视频列表 |