97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
亚洲第一视频在线播放,天天操夜夜摸,精品嫩草
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-STK18/BF594 Conjugated antibody (bs-6393R-BF594)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-6393R-BF594
英文名稱 Rabbit Anti-STK18/BF594 Conjugated antibody
中文名稱 BF594標記的絲氨酸/蘇氨酸蛋白激酶18
別    名 PLK 4; PLK-4; PLK4; PLK4_HUMAN; Polo like Kinase 4; Polo-like kinase 4; Protein serine/threonine kinase; SAK; Serine/Threonine Kinase 18; Serine/threonine kinase; Serine/threonine protein kinase 18; Serine/threonine protein kinase PLK4; Serine/threonine protein kinase Sak; Serine/threonine-protein kinase 18; Serine/threonine-protein kinase PLK4; Serine/threonine-protein kinase SAK; Snk Akin Kinase; STK 18; STK18.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  免疫學  信號轉導  細胞周期蛋白  激酶和磷酸酶  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 108kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PLK4/STK18
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Serine/threonine-protein kinase that plays a central role in centriole duplication. Able to trigger procentriole formation on the surface of the parental centriole cylinder, leading to the recruitment of centriole biogenesis proteins such as SASS6, CENPJ/CPAP, CP110, CEP135 and gamma-tubulin. When overexpressed, it is able to induce centrosome amplification through the simultaneous generation of multiple procentrioles adjoining each parental centriole during S phase. Its central role in centriole replication suggests a posible role in tumorigenesis, centrosome aberrations being frequently observed in tumors. Also involved in trophoblast differentiation by phosphorylating HAND1, leading to disrupt the interaction between HAND1 and MDFIC and activate HAND1. Phosphorylates CDC25C and CHEK2/CHK2.

Function:
Serine/threonine-protein kinase that plays a central role in centriole duplication. Able to trigger procentriole formation on the surface of the parental centriole cylinder, leading to the recruitment of centriole biogenesis proteins such as SASS6, CENPJ/CPAP, CP110, CEP135 and gamma-tubulin. When overexpressed, it is able to induce centrosome amplification through the simultaneous generation of multiple procentrioles adjoining each parental centriole during S phase. Its central role in centriole replication suggests a posible role in tumorigenesis, centrosome aberrations being frequently observed in tumors. Also involved in trophoblast differentiation by phosphorylating HAND1, leading to disrupt the interaction between HAND1 and MDFIC and activate HAND1. Phosphorylates CDC25C and CHEK2.

Subunit:
Homodimer. Interacts with CEP152 (via N-terminus).

Subcellular Location:
Cytoplasm, cytoskeleton, centrosome, centriole. Nucleus, nucleolus.

Post-translational modifications:
Ubiquitinated; leading to its degradation by the proteasome.
Tyrosine-phosphorylated by TEC.

Similarity:
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.

Database links:

Entrez Gene: 10733 Human

Entrez Gene: 20873 Mouse

Entrez Gene: 310344 Rat

SwissProt: O00444 Human

SwissProt: Q64702 Mouse

SwissProt: B2GUY1 Rat

Unigene: 172052 Human

Unigene: 3794 Mouse

Unigene: 14848 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 国产大片中文字幕在线观看 | 91精品片| aaa在线| 3344www成人| 18禁无遮挡免费视频网站 | 中出乱码av亚洲精品久久天堂 | 日本激情视频在线播放 | 免费aa大片 | free性欧美1819hd| 国产精品久久久久9999 | 日本少妇高潮叫床声 | 国产线观看免费观看 | 日本少妇做爰全过程二区 | 上锁的房间中国版免费 | 国产精品va无码欧美二区 | 黄色一级久久 | 久久精品成人免费观看三 | 亚洲综合在线另类色区奇米 | 在线一级观看 | 国产AV无码专区亚洲精品 | 青青草华人在线 | 国产精品久久99精品毛片三a | 亚洲首页一区任你躁XXXXX | 精品成人免费 | 午夜剧场成年 | 日韩精品区一区二区三vr | 日韩福利 | 亚洲国产播放 | yy6080午夜我不卡 | 亚洲精品国产精品久久99 | 中文精品一区二区三区四区 | 日日操日日爽 | 把女的下面扒开添视频 | 手机在线黄色网址 | 台湾绝版午夜裸体写真秀 | 欧美老人与小伙子性生交 | 日韩资源在线观看 | 久久久久久久久艹 | 偷拍东北熟女BBWW | www香蕉| 美女一区二区三区视频 |