97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
日韩av手机观看,免费观看一级特黄欧美大片,2018国产在线
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-CDCA5/Cy7 Conjugated antibody (bs-7717R-Cy7)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-7717R-Cy7
英文名稱 Rabbit Anti-CDCA5/Cy7 Conjugated antibody
中文名稱 Cy7標記的細胞分裂周期相關蛋白5抗體
別    名 Cell division cycle associated protein 5; MGC16386; p35; Sororin; CDCA5_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  染色質和核信號  細胞周期蛋白  細胞分化  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse,  (predicted: Rat, Dog, Pig, Cow, Horse, Rabbit, )
產品應用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 28kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CDCA5
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Sororin, also designated cell division cycle-associated protein 5 (CDCA5) or p35, functions as a regulator of sister chromatid cohesion during mitosis. It interacts with the APC/C complex and is found in a complex consisting of cohesion components SCC-112, MC1L1, SMC3L1, RAD21 and APRIN. The deduced human and mouse Sororin proteins consist of 252 and 264 amino acid residues, respectively, and both contain a KEN box for APC-dependent ubiquitination. Reserach demonstrates a punctated nuclear distribution of Sororin during interphase and a diffuse distribution throughout the cell during mitosis. There is no apparent concentration of Sororin on chromatin in mitotic cells and Sororin levels decrease in synchronized HeLa cells during interphase. The Sororin gene maps to chromosome 11q12.1.

Function:
CDCA5 is a regulator of sister chromatid cohesion in mitosis. It may act by regulating the ability of the cohesin complex to mediate sister chromatid cohesion, perhaps by altering the nature of the interaction of cohesin with the chromosomes. CDCA5 interacts with the APC/C complex and is found in a complex with the cohesin components SMC1L1, SMC3L1, RAD21, PDS5A/APRIN and PDS5B/SCC-112.

Subunit:
Interacts with the APC/C complex (By similarity). Interacts with the chromatin-bound cohesin complex; the interaction is indirect, occurs after DNA replication and requires acetylation of the cohesin component SMC3. Interacts (via the FGF motif) with PDS5A and PDS5B; the interaction is direct and prevents the interaction of PDS5A with WAPAL.

Subcellular Location:
Nuclear.

Post-translational modifications:
Phosphorylated. Phosphorylation, as cells enter mitosis, disrupts the interaction with PDS5A and relieves the inhibition of WAPAL by CDCA5.
Ubiquitinated by the APC/C complex in G1, leading to its degradation (Probable).

Similarity:
Belongs to the sororin family.

Database links:
UniProtKB/Swiss-Prot: Q96FF9.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: aaa大片在线观看 | 久久久久久成人毛片免费看 | 日韩亚洲欧美在线 | 亚洲国产精品一区二区第一页 | 国产日产免费高清欧美一区 | 青天衙门高清第一部免费观看 | 黄色片在线免费 | 色淫影院 | 国产亚洲精品欧洲在线观看 | 亚洲第一成网 | 欧美日产国产新一区 | 免费大片AV手机看片高清 | 免费视频网站一区二区三区 | 年轻的朋友6韩剧免费 | 亚洲精品男女 | 免费视频18上在线观看 | 美女大胆作爱全过程 | www.免费av| 少妇撒尿一区二区在线视频 | 日本少妇高潮喷水视频 | 99视频免费 | 国产成人啪精品视频免费网站 | 国产草莓视频无码A在线观看 | 狠狠色婷婷久久一区二区三区91 | 成版人性视频 | 欧美精品高清 | 一本大道久久加勒比香蕉 | 成人免费视频xbxb入口 | av毛片一区二区三区 | JIZZ成熟少妇 | 伊人久久精品欧洲综合网 | 成人免费视频一区二区三区 | 久草精品在线 | 国产第一页福利影院 | 性xxxx欧美老妇506070 | 欧美中文字幕在线 | 亚洲欧美日韩精品永久在线 | 国产一级精品片 | 大陆av在线播放 | 麻豆av观看 | 麻豆精品国产入口 |