97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
蜜芽AⅤ色欲AV浪潮夜夜嗨,成人福利片网站,国产网友自拍视频
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-CDCA5/BF350 Conjugated antibody (bs-7717R-BF350)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-7717R-BF350
英文名稱 Rabbit Anti-CDCA5/BF350 Conjugated antibody
中文名稱 BF350標記的細胞分裂周期相關蛋白5抗體
別    名 Cell division cycle associated protein 5; MGC16386; p35; Sororin; CDCA5_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  染色質和核信號  細胞周期蛋白  細胞分化  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse,  (predicted: Rat, Dog, Pig, Cow, Horse, Rabbit, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 28kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CDCA5
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Sororin, also designated cell division cycle-associated protein 5 (CDCA5) or p35, functions as a regulator of sister chromatid cohesion during mitosis. It interacts with the APC/C complex and is found in a complex consisting of cohesion components SCC-112, MC1L1, SMC3L1, RAD21 and APRIN. The deduced human and mouse Sororin proteins consist of 252 and 264 amino acid residues, respectively, and both contain a KEN box for APC-dependent ubiquitination. Reserach demonstrates a punctated nuclear distribution of Sororin during interphase and a diffuse distribution throughout the cell during mitosis. There is no apparent concentration of Sororin on chromatin in mitotic cells and Sororin levels decrease in synchronized HeLa cells during interphase. The Sororin gene maps to chromosome 11q12.1.

Function:
CDCA5 is a regulator of sister chromatid cohesion in mitosis. It may act by regulating the ability of the cohesin complex to mediate sister chromatid cohesion, perhaps by altering the nature of the interaction of cohesin with the chromosomes. CDCA5 interacts with the APC/C complex and is found in a complex with the cohesin components SMC1L1, SMC3L1, RAD21, PDS5A/APRIN and PDS5B/SCC-112.

Subunit:
Interacts with the APC/C complex (By similarity). Interacts with the chromatin-bound cohesin complex; the interaction is indirect, occurs after DNA replication and requires acetylation of the cohesin component SMC3. Interacts (via the FGF motif) with PDS5A and PDS5B; the interaction is direct and prevents the interaction of PDS5A with WAPAL.

Subcellular Location:
Nuclear.

Post-translational modifications:
Phosphorylated. Phosphorylation, as cells enter mitosis, disrupts the interaction with PDS5A and relieves the inhibition of WAPAL by CDCA5.
Ubiquitinated by the APC/C complex in G1, leading to its degradation (Probable).

Similarity:
Belongs to the sororin family.

Database links:
UniProtKB/Swiss-Prot: Q96FF9.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 蜜臀亚洲AV无码精品国产午夜. | 国产精品婷婷不卡久久久 | 91亚洲精品第一 | 无码精品人妻一区二区三区老牛 | 久久日韩精品一区鲁大师 | 久久青青草原国产精品最新片 | 国产一片姪乱洗澡 | 亚洲AV日韩AV国内 | 精品福利视频一区二区三区 | 中文字幕无码乱码人妻系列蜜桃 | 91视频九色欧美 | 免费网站www在线观看 | av中文字| 亚洲一二三四在线 | 亚洲一区二区三区不卡国产欧美 | 激情另类小说区图片区视频区 | 日本精品一区二区三区四区 | gogogo高清在线观看中文 | 伊人青青操 | 亚洲女同成av人片在线观看 | 男女超爽视频免费播放 | 国内免费视频成人精品 | 天天弄天天模 | 五月丁香六月激情综合在线视频 | 国产v亚洲v天堂无码 | 精品婷婷久久 | 69久久夜色精品国产69蝌蚪网 | 日韩第一夜 | 国产丝袜一区视频在线观看 | 国内自拍偷拍一区 | 一区二区免费在线观看 | 狠狠躁躁夜夜躁波多野结依 | 亚洲日韩欧美一区久久久久我 | 91免费黄视频 | 国产在线观看无码一区二区三区 | 久久久久国产精品一区二区三区 | 女同久久精品国产99国产精品网站 | 无码精品A∨在线观看中文 国产午夜精品片一区二区三区 | 免费在线一级片 | 农村夫妇大白天啪啪 | 成年人在线免费观看热视频 |