97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
黄色片视频免费,国产操穴视频,女人第一次一男一女毛片
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-CDCA5/BF594 Conjugated antibody (bs-7717R-BF594)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-7717R-BF594
英文名稱 Rabbit Anti-CDCA5/BF594 Conjugated antibody
中文名稱 BF594標記的細胞分裂周期相關蛋白5抗體
別    名 Cell division cycle associated protein 5; MGC16386; p35; Sororin; CDCA5_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  染色質和核信號  細胞周期蛋白  細胞分化  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse,  (predicted: Rat, Dog, Pig, Cow, Horse, Rabbit, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 28kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CDCA5
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Sororin, also designated cell division cycle-associated protein 5 (CDCA5) or p35, functions as a regulator of sister chromatid cohesion during mitosis. It interacts with the APC/C complex and is found in a complex consisting of cohesion components SCC-112, MC1L1, SMC3L1, RAD21 and APRIN. The deduced human and mouse Sororin proteins consist of 252 and 264 amino acid residues, respectively, and both contain a KEN box for APC-dependent ubiquitination. Reserach demonstrates a punctated nuclear distribution of Sororin during interphase and a diffuse distribution throughout the cell during mitosis. There is no apparent concentration of Sororin on chromatin in mitotic cells and Sororin levels decrease in synchronized HeLa cells during interphase. The Sororin gene maps to chromosome 11q12.1.

Function:
CDCA5 is a regulator of sister chromatid cohesion in mitosis. It may act by regulating the ability of the cohesin complex to mediate sister chromatid cohesion, perhaps by altering the nature of the interaction of cohesin with the chromosomes. CDCA5 interacts with the APC/C complex and is found in a complex with the cohesin components SMC1L1, SMC3L1, RAD21, PDS5A/APRIN and PDS5B/SCC-112.

Subunit:
Interacts with the APC/C complex (By similarity). Interacts with the chromatin-bound cohesin complex; the interaction is indirect, occurs after DNA replication and requires acetylation of the cohesin component SMC3. Interacts (via the FGF motif) with PDS5A and PDS5B; the interaction is direct and prevents the interaction of PDS5A with WAPAL.

Subcellular Location:
Nuclear.

Post-translational modifications:
Phosphorylated. Phosphorylation, as cells enter mitosis, disrupts the interaction with PDS5A and relieves the inhibition of WAPAL by CDCA5.
Ubiquitinated by the APC/C complex in G1, leading to its degradation (Probable).

Similarity:
Belongs to the sororin family.

Database links:
UniProtKB/Swiss-Prot: Q96FF9.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 8050一级毛片 | 欧美精品在线不卡 | 在线不卡欧美精品一区二区三区 | 亚洲精品中国国产嫩草影院美女 | 久草国内| 欧洲熟妇乱xxxxx大屁股7 | 91精品论坛| 免费人成视频在线观看播放网站 | 亚洲色成人四虎在线观看 | 亚洲日韩在线中文字幕第一页 | 51精品国产人成在线观看 | 激情久久久久久久 | 欧美视频精品全部免费观看 | 吃奶呻吟打开双腿做受视频 | 亚洲精品久久久久无码精品 | 精品亚洲一区二区 | 久久精品一区二区三区四区 | 日韩大片在线观看 | 欧美不卡视频 | 日本xxxx裸体xxxx视频大全 | 久久精品女人毛片国产 | 成人春色视频www | 国产成人一级在线观看 | 视频二区三区 | 久久久91精品国产一区二区精品 | 国产麻豆精品福利在线观看 | 黄色动态图视频 | 色综合视频一区二区三区44 | 久久国产精品精品国产 | 国产欧美一区二区白浆黑人 | 久久久久久久久18久久久 | 脱了老师内裤猛烈进入在线观看 | 亚洲国产精品久久久久秋霞不卡 | 精品人妻无码专区在中文字幕 | 两个人看的www免费 国产一区二区三区18 | 深夜福利成人 | 亚洲欧洲一区二区三区在线 | 免费大片AV手机看片高清 | 蜜桃麻豆WWW久久囤产精品 | 小小拗女一区二区三区 | 日韩新片在线观看 |