97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
免费高清特色大片在线观看,亚洲日韩精品A∨片无码加勒比,成人黄色免费网站
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-Separase/Cy5 Conjugated antibody (bs-7732R-Cy5)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-7732R-Cy5
英文名稱 Rabbit Anti-Separase/Cy5 Conjugated antibody
中文名稱 Cy5標記的外紡錘體極樣蛋白1抗體
別    名 Caspase like protein ESPL1; ESP 1; ESP1; ESP-1; ESPL 1; ESPL1; ESPL-1; Extra spindle poles like 1; Extra spindle poles like 1 protein; Separin; Similar to fission yeast cut1and gene; SSE; Separase; ESPL1_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  細胞周期蛋白  細胞分化  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 233kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Separase
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Stable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance. In vertebrates, sister chromatid cohesion is released in 2 steps via distinct mechanisms. The first step involves phosphorylation of STAG1 (MIM 604358) or STAG2 (MIM 300826) in the cohesin complex. The second step involves cleavage of the cohesin subunit SCC1 (RAD21; MIM 606462) by ESPL1, or separase, which initiates the final separation of sister chromatids (Sun et al., 2009 [PubMed 19345191]).[supplied by OMIM, Nov 2010].

Function:
Caspase-like protease, which plays a central role in the chromosome segregation by cleaving the SCC1/RAD21 subunit of the cohesin complex at the onset of anaphase. During most of the cell cycle, it is inactivated by different mechanisms.

Subunit:
Interacts with PTTG1. Interacts with RAD21.

Subcellular Location:
Cytoplasm. Nucleus.

Post-translational modifications:
Autocleaves. This function, which is not essential for its protease activity, is unknown.
Phosphorylated by CDK1. There are 8 Ser/Thr phosphorylation sites. Among them, Ser-1126 phosphorylation is the major site, which conducts to the enzyme inactivation.

Similarity:
Belongs to the peptidase C50 family.

Database links:

Entrez Gene: 9700 Human

Entrez Gene: 105988 Mouse

Omim: 604143 Human

SwissProt: Q14674 Human

SwissProt: P60330 Mouse

Unigene: 153479 Human

Unigene: 288324 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 国产精品综合在线观看 | 久久久久人妻精品区一三寸 | 国产色网站 | 国产成人综合激情视频在线观看 | 日韩欧美毛片免费观看 | 日日爱668 | 四虎影音 | 日本黄色片在线免费观看 | 欧美XXXXX高潮喷水麻豆 | 18无遮挡啪啪无码网站免费看 | 欧美精品在线视频观看 | 日韩精品免费看 | 一区二区视频免费看 | 狠狠操社区 | 天天摸日日添狠狠添婷婷 | av中文字幕最新在线观看 | 国产拍精品一二三 | 欧洲成人午夜精品无码区久久 | 国产精品久久精品 | 亚洲精品视频成人 | 国产午夜精品免费一区二区三区 | 91丨九色丨丰满人妖 | 乱爱性全过程免费视频 | 桃色av一区二区 | 久久精品精品 | 日韩第九页 | 国产精妇在线观看第一区 | 亚洲第一页在线视频 | 日本黄色一级片免费看 | 亚洲精品中国国产嫩草影院美女 | 欧美日韩精品一区二区三区在线观看 | 欧美日韩不卡一区二区 | 国产免费一区二区三区在线观看 | 美女内射无套日韩免费播放 | 午夜影院 | 天天操天天干天天爽 | 欧美视频免费看 | www视频在线免费观看 | 被两个两个黑人吃奶4P | 色啪视频| 国产麻豆剧传媒精品AV |