97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
日产精品一二三区,免费成人动漫网站,欧美亚洲影院
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-Separase/Cy7 Conjugated antibody (bs-7732R-Cy7)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-7732R-Cy7
英文名稱 Rabbit Anti-Separase/Cy7 Conjugated antibody
中文名稱 Cy7標記的外紡錘體極樣蛋白1抗體
別    名 Caspase like protein ESPL1; ESP 1; ESP1; ESP-1; ESPL 1; ESPL1; ESPL-1; Extra spindle poles like 1; Extra spindle poles like 1 protein; Separin; Similar to fission yeast cut1and gene; SSE; Separase; ESPL1_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  細胞周期蛋白  細胞分化  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, )
產品應用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 233kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Separase
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Stable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance. In vertebrates, sister chromatid cohesion is released in 2 steps via distinct mechanisms. The first step involves phosphorylation of STAG1 (MIM 604358) or STAG2 (MIM 300826) in the cohesin complex. The second step involves cleavage of the cohesin subunit SCC1 (RAD21; MIM 606462) by ESPL1, or separase, which initiates the final separation of sister chromatids (Sun et al., 2009 [PubMed 19345191]).[supplied by OMIM, Nov 2010].

Function:
Caspase-like protease, which plays a central role in the chromosome segregation by cleaving the SCC1/RAD21 subunit of the cohesin complex at the onset of anaphase. During most of the cell cycle, it is inactivated by different mechanisms.

Subunit:
Interacts with PTTG1. Interacts with RAD21.

Subcellular Location:
Cytoplasm. Nucleus.

Post-translational modifications:
Autocleaves. This function, which is not essential for its protease activity, is unknown.
Phosphorylated by CDK1. There are 8 Ser/Thr phosphorylation sites. Among them, Ser-1126 phosphorylation is the major site, which conducts to the enzyme inactivation.

Similarity:
Belongs to the peptidase C50 family.

Database links:

Entrez Gene: 9700 Human

Entrez Gene: 105988 Mouse

Omim: 604143 Human

SwissProt: Q14674 Human

SwissProt: P60330 Mouse

Unigene: 153479 Human

Unigene: 288324 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 久久久久视 | 免费观看18禁无遮挡真人网站 | 国产99视频精品免费观看6 | 极品美女Aⅴ在线观看 | 国精品无码一区二区三区在线 | 亚洲第一天堂久久 | 国产爽爽久久影院潘金莲 | 强壮公弄得小薇高潮 | 在线观看av一区二区 | 日韩精品一区二区三 | 无限看片的视频高清在线 | 久久久久久久波多野结衣高潮 | 国产无遮挡无码视频免费软件 | 成人影院免费942cm | 免费黄色在线 | 精品综合久久久久久888蜜芽 | 日韩www | 亚洲无码专区三区在线观看 | 黄色一级片免费 | 前夜40集连续剧免费观看国语高清 | 亚洲三区欧美一区国产二区 | 九一欧美 | 国产日韩欧美亚洲 | 绿奴vk| 国产精品久久久久久久亚洲按摩 | 久久夜色精品国产噜噜亚洲AV | 香港三级韩国三级日本三级 | 国产偷久久一级精品av小说 | 男人插女人逼逼视频 | 免费精品国产福利片 | 成人毛片在线 | 精品一区二区三区视频日产 | 精品国产乱码久久久久久久 | 亚洲爆乳成AV人在线视水卜 | 精品国产第一福利网站 | 亚洲一级视频在线观看 | 西西人体444WWW大胆无码视频 | 国产91小视频在线观看 | 91丨九色丨黑人外教 | 久久22| 国产乱淫片视频 |