97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
天天色伊人,2020国产成人综合网,国产免费又爽又色又粗视频
Rabbit Anti-Separase/PE-Cy3 Conjugated antibody (bs-7732R-PE-Cy3)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-7732R-PE-Cy3
英文名稱 Rabbit Anti-Separase/PE-Cy3 Conjugated antibody
中文名稱 PE-Cy3標(biāo)記的外紡錘體極樣蛋白1抗體
別    名 Caspase like protein ESPL1; ESP 1; ESP1; ESP-1; ESPL 1; ESPL1; ESPL-1; Extra spindle poles like 1; Extra spindle poles like 1 protein; Separin; Similar to fission yeast cut1and gene; SSE; Separase; ESPL1_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  細(xì)胞周期蛋白  細(xì)胞分化  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 233kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Separase
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Stable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance. In vertebrates, sister chromatid cohesion is released in 2 steps via distinct mechanisms. The first step involves phosphorylation of STAG1 (MIM 604358) or STAG2 (MIM 300826) in the cohesin complex. The second step involves cleavage of the cohesin subunit SCC1 (RAD21; MIM 606462) by ESPL1, or separase, which initiates the final separation of sister chromatids (Sun et al., 2009 [PubMed 19345191]).[supplied by OMIM, Nov 2010].

Function:
Caspase-like protease, which plays a central role in the chromosome segregation by cleaving the SCC1/RAD21 subunit of the cohesin complex at the onset of anaphase. During most of the cell cycle, it is inactivated by different mechanisms.

Subunit:
Interacts with PTTG1. Interacts with RAD21.

Subcellular Location:
Cytoplasm. Nucleus.

Post-translational modifications:
Autocleaves. This function, which is not essential for its protease activity, is unknown.
Phosphorylated by CDK1. There are 8 Ser/Thr phosphorylation sites. Among them, Ser-1126 phosphorylation is the major site, which conducts to the enzyme inactivation.

Similarity:
Belongs to the peptidase C50 family.

Database links:

Entrez Gene: 9700 Human

Entrez Gene: 105988 Mouse

Omim: 604143 Human

SwissProt: Q14674 Human

SwissProt: P60330 Mouse

Unigene: 153479 Human

Unigene: 288324 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.kastlife.cn 北京博奧森生物技術(shù)有限公司
通過國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
主站蜘蛛池模板: 91精品国产综合久久小仙女图片 | 午夜性生大片免费观看 | 精品人伦一区二区三区蜜桃视频 | 亚洲xxxx3d | 521av永久免费网 | 成人欧美一区二区三区小说 | 国产二级一片内射视频播放 | 国产日本在线视频 | 久久久久亚洲AV成人片无码 | 中字幕久久久人妻熟女天美传媒 | 大香伊蕉最新视频 | 国产综合精品一区二区 | 国产一区免费看 | 男女性高爱潮免费网站 | 国产成人啪精品午夜网站a片免费 | 国产一二三区在线视频 | 91精品国产综合久久久亚洲 | 亚洲人成激情在线播放国 | 大地资源影院在线播放 | 国产一区二区精品久久岳 | 日本一区二区三区精品福利视频 | 不戴奶罩的教师水卜樱在线观看 | 国产激情视频一区二区 | 日韩精品一区二区三区蜜臀 | 久久艹人人 | 国产伦精品一区二区三区网站 | 麻豆福利网 | 中文字幕在线一区 | 欧美性受xxxx黑人x丫x性爽 | 日韩av高清在线 | 韩国av一区二区三区四区 | 少妇高潮毛片 | 橘梨纱av一区二区三区在线观看 | 老熟女激烈的高潮 | 苍井空亚洲精品AA片在线播放 | 亚洲精品无码一区二区三区污 | 一级片免费在线看 | 四色激情网 | 大地资源二在线观看官网 | 久久久无码精品亚洲欧美 | 欧美多人乱大交xxxxx |