97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
日产乱码一二三区别免费演员表,日本欧美www视频网站,韩国18禁男男黄网站
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-Separase/PE-Cy5.5 Conjugated antibody (bs-7732R-PE-Cy5.5)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-7732R-PE-Cy5.5
英文名稱 Rabbit Anti-Separase/PE-Cy5.5 Conjugated antibody
中文名稱 PE-Cy5.5標記的外紡錘體極樣蛋白1抗體
別    名 Caspase like protein ESPL1; ESP 1; ESP1; ESP-1; ESPL 1; ESPL1; ESPL-1; Extra spindle poles like 1; Extra spindle poles like 1 protein; Separin; Similar to fission yeast cut1and gene; SSE; Separase; ESPL1_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  細胞周期蛋白  細胞分化  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 233kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Separase
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Stable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance. In vertebrates, sister chromatid cohesion is released in 2 steps via distinct mechanisms. The first step involves phosphorylation of STAG1 (MIM 604358) or STAG2 (MIM 300826) in the cohesin complex. The second step involves cleavage of the cohesin subunit SCC1 (RAD21; MIM 606462) by ESPL1, or separase, which initiates the final separation of sister chromatids (Sun et al., 2009 [PubMed 19345191]).[supplied by OMIM, Nov 2010].

Function:
Caspase-like protease, which plays a central role in the chromosome segregation by cleaving the SCC1/RAD21 subunit of the cohesin complex at the onset of anaphase. During most of the cell cycle, it is inactivated by different mechanisms.

Subunit:
Interacts with PTTG1. Interacts with RAD21.

Subcellular Location:
Cytoplasm. Nucleus.

Post-translational modifications:
Autocleaves. This function, which is not essential for its protease activity, is unknown.
Phosphorylated by CDK1. There are 8 Ser/Thr phosphorylation sites. Among them, Ser-1126 phosphorylation is the major site, which conducts to the enzyme inactivation.

Similarity:
Belongs to the peptidase C50 family.

Database links:

Entrez Gene: 9700 Human

Entrez Gene: 105988 Mouse

Omim: 604143 Human

SwissProt: Q14674 Human

SwissProt: P60330 Mouse

Unigene: 153479 Human

Unigene: 288324 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 极品美女a诱v惑在线观看免费 | 中国美女a级毛片 | 国产一区二区高清在线观看 | 久久久精品小视频 | 成年肉动漫在线观看无码 | 久久精品国产亚洲aⅴ瑜伽 操处女逼小说 | 扒开双腿猛进入喷水高潮视频 | 亚洲女同成av人片在线观看 | 二次元人物桶二次元人物免费 | 很黄的网站在线观看 | 橘梨纱av一区二区三区在线观看 | 办公室扒开奶罩揉吮奶头AV | 日本三级黄网站 | 野花在线观看免费 | 优酷在线观看 | 精品一区二区中文字幕 | 欧美色插 | 孩交精品XXXX视频视频 | 国语国产精精品国产国语清晰对话 | 成人午夜做爰视频免费看 | 国产亚洲一区二区三区四区 | aⅴ免费一区二区三区 | 91久久精品久久国产性色也91 | 北条一二三区 | 日韩一级黄色大片 | 美女诱惑一区二区 | 果冻传媒2021精品一区 | 91精品在线视频观看 | a级大片免费观看 | 蜜臀久久99精品久久久久久 | 国外AV无码精品国产精品 | 欧美xxxxxx片免费播放软件 | 精品国产乱码91久久久久久网站 | 波多野结衣在线视频一区二区三区 | 欧美在线视频免费看 | 伊人久久大香线蕉av最新 | 日韩天堂在线观看 | 91精品久久久久久久久久不卡 | 成人综合激情 | 欧美精品一区二区久久久 | H无码精品动漫在线观看导航 |