97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
日韩黄色动漫,国产91会所女技师在线观,大陆一级毛片免费观看
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-Separase/BF594 Conjugated antibody (bs-7732R-BF594)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-7732R-BF594
英文名稱 Rabbit Anti-Separase/BF594 Conjugated antibody
中文名稱 BF594標記的外紡錘體極樣蛋白1抗體
別    名 Caspase like protein ESPL1; ESP 1; ESP1; ESP-1; ESPL 1; ESPL1; ESPL-1; Extra spindle poles like 1; Extra spindle poles like 1 protein; Separin; Similar to fission yeast cut1and gene; SSE; Separase; ESPL1_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  細胞周期蛋白  細胞分化  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 233kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Separase
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Stable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance. In vertebrates, sister chromatid cohesion is released in 2 steps via distinct mechanisms. The first step involves phosphorylation of STAG1 (MIM 604358) or STAG2 (MIM 300826) in the cohesin complex. The second step involves cleavage of the cohesin subunit SCC1 (RAD21; MIM 606462) by ESPL1, or separase, which initiates the final separation of sister chromatids (Sun et al., 2009 [PubMed 19345191]).[supplied by OMIM, Nov 2010].

Function:
Caspase-like protease, which plays a central role in the chromosome segregation by cleaving the SCC1/RAD21 subunit of the cohesin complex at the onset of anaphase. During most of the cell cycle, it is inactivated by different mechanisms.

Subunit:
Interacts with PTTG1. Interacts with RAD21.

Subcellular Location:
Cytoplasm. Nucleus.

Post-translational modifications:
Autocleaves. This function, which is not essential for its protease activity, is unknown.
Phosphorylated by CDK1. There are 8 Ser/Thr phosphorylation sites. Among them, Ser-1126 phosphorylation is the major site, which conducts to the enzyme inactivation.

Similarity:
Belongs to the peptidase C50 family.

Database links:

Entrez Gene: 9700 Human

Entrez Gene: 105988 Mouse

Omim: 604143 Human

SwissProt: Q14674 Human

SwissProt: P60330 Mouse

Unigene: 153479 Human

Unigene: 288324 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 一区二区三区四区视频免费观看 | 欧美视频在线观看 | 久草不卡视频 | 九九热线视频只有这里最精品 | 九九福利视频 | 欧美日韩中文字幕一区二区高清 | 国产精品嫩草99av在线 | 中文字幕久精品免费视频 | 亚洲国产成人va在线观看 | 日本黄色激情片 | 国产各种高潮合集在线观看 | 欧美精品一国产成人综合久久 | 欧美日韩亚洲中文字幕二区 | 久久综合久久综合九色 | 桃子视频在线观看高清免费视频 | 日韩中文字幕无码高清毛片 | 久久大香国产成人AV | 999视频精品 | 好看的日韩精品 | 毛片基地美国 | 在线看片无码永久免费AV | 日本波多野结衣在线 | 人妻无码中文久久久久专区 | 国产一级淫片a按摩推澡按摩 | 中文字幕日韩高清2024 | 久久九九热 | 日韩一级免费在线观看 | 公和我做好爽添在厨房 | 人妻三级日本三级日本三级极 | 全黄a免费一级毛片人人爱 久久久久偷看国产亚洲87 | 国产成人免费一区二区三区 | 国产熟女一区二区三区四区五区 | 中文字幕一区二区三区视频 | 天天玩天天操天天干 | 精品在线观看一区二区 | 国产高清精品在线观看 | 亚洲高清视频在线 | 亚洲精品美女视频在线观看 | 麻豆视频入口 | 77777日本少妇久7黄绝片 | 天天综合网网欲色 |