97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
最新日韩免费,欧美搡BBBBB搡BBBBB,91自啪
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-CEP55/Gold Conjugated antibody (bs-7742R-Gold)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產品編號 bs-7742R-Gold
英文名稱 Rabbit Anti-CEP55/Gold Conjugated antibody
中文名稱 膠體金標記的中心體蛋白55kDa抗體
別    名 C10orf3; Centrosomal protein 55kDa; Centrosomal protein of 55 kDa; CEP 55; FLJ10540; Up regulated in colon cancer 6; URCC 6; URCC6; CEP55_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 細胞生物  細胞周期蛋白  細胞分化  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse,  (predicted: Human, Rat, Dog, Pig, Horse, Sheep, )
產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 54kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CEP55
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產品介紹 background:
CEP55 (Centrosomal protein 55kDa) is essential for mitotic exit and cytokinesis. It is not required for microtubule nucleation.

Function:
Plays a role in mitotic exit and cytokinesis. Not required for microtubule nucleation. Recruits PDCD6IP and TSG101 to midbody during cytokinesis.

Subunit:
Homodimer. Interacts (phosphorylated on Ser-425 and Ser-428) with PLK1. Interacts with AKAP9; the interaction occurs in interphase and is lost upon mitotic entry. Interacts with PCNT; the interaction occurs in interphase and is lost upon mitotic entry. Interacts with PDCD6IP; the interaction is direct; CEP55 binds PDCD6IP in a 2:1 stoechiometry; PDCD6IP competes with TSG101 for the same binding site. Interacts with TSG101; TSG101 competes with PDCD6IP for the same binding site; interaction is required for cytokinesis but not for viral budding. Interacts with MVB12A, VPS37B, VPS37C and VPS28.

Subcellular Location:
Cytoplasm, cytoskeleton, centrosome, centriole. Cytoplasm, cytoskeleton, centrosome. Cleavage furrow. Midbody. Note=Present at the centrosomes at interphase. A small portion is associated preferentially with the mother centriole, whereas the majority localizes to the pericentriolar material. During mitosis, loss of affinity for the centrosome at the onset of prophase and diffusion throughout the cell. This dissociation from the centrosome is phosphorylation-dependent. May remain localized at the centrosome during mitosis in certain cell types. Appears at the cleavage furrow in late anaphase and in the midbody in cytokinesis.

Tissue Specificity:
Widely expressed, mostly in proliferative tissues. Highly expressed in testis. Intermediate levels in adult and fetal thymus, as well as in various cancer cell lines. Low levels in different parts of the digestive tract, bone marrow, lymph nodes, placenta, fetal heart and fetal spleen. Hardly detected in brain.

Post-translational modifications:
There is a hierachy of phosphorylation, where both Ser-425 and Ser-428 are phosphorylated at the onset of mitosis, prior to Ser-436. Phosphorylation at Ser-425 and Ser-428 is required for dissociation from the centrosome at the G2/M boundary. Phosphorylation at the 3 sites, Ser-425, Ser-428 and Ser-436, is required for protein function at the final stages of cell division to complete cytokinesis successfully.

Database links:

Entrez Gene: 55165 Human

Entrez Gene: 74107 Mouse

Entrez Gene: 294074 Rat

Omim: 610000 Human

SwissProt: Q53EZ4 Human

SwissProt: Q8BT07 Mouse

SwissProt: Q4V7C8 Rat

Unigene: 14559 Human

Unigene: 9916 Mouse

Unigene: 90818 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 内射白嫩少妇超碰 | 久久亚洲美女视频 | 成年人中文字幕在线观看 | 亚洲日韩中文字幕天堂不卡 | 97人妻人人做人碰人人添 | 亚洲中文字幕久久精品无码va | 一本久久A精品一区二区 | 国产在线啪| 亚洲永久精品av在线观看 | 国内精品久久久久影院优 | 丝袜无码一区二区三区 | 狠狠成人 | 久久久久久亚洲 | 3p少妇全程露脸过瘾呀 | 国产一区二区丁香婷婷 | 女人和拘做受全程看免费软件 | 一级卡毛片 | 麻豆国产手机福利看片 | 国产精品久久久不卡 | 日韩新片在线观看 | 欧美群交射精内射颜射潮喷 | 多人调教到高潮失禁h重口文 | 亚洲成人伊人 | 国产一级桃视频播放 | 久久久久久久人妻无码中文字幕爆 | 亚洲啪啪av无码片 | aaa级精品久久久国产片 | 成人黄色免费观看 | 日本黄色一级片免费看 | 午夜性刺激免费看视频 | 日本黄色录像视频 | 欧美日本中文 | 国内自产拍自拍A免费毛片 无码人妻精品一区二区三区久久 | 最近中文AV字幕在线中文 | 亚洲伦理偷拍 | 九草视频在线观看 | 欧美国产三级 | 无码日韩精品一区二区免费 | 区区久久久狼 | 色久悠悠在线观看 | 国产欧美久久一区二区三区 |