97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
国产极品一区二区三区,久久九九视频,巴中文旅集团
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-CEP55/APC Conjugated antibody (bs-7742R-APC)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-7742R-APC
英文名稱 Rabbit Anti-CEP55/APC Conjugated antibody
中文名稱 APC標記的中心體蛋白55kDa抗體
別    名 C10orf3; Centrosomal protein 55kDa; Centrosomal protein of 55 kDa; CEP 55; FLJ10540; Up regulated in colon cancer 6; URCC 6; URCC6; CEP55_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  細胞周期蛋白  細胞分化  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse,  (predicted: Human, Rat, Dog, Pig, Horse, Sheep, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 54kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CEP55
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
CEP55 (Centrosomal protein 55kDa) is essential for mitotic exit and cytokinesis. It is not required for microtubule nucleation.

Function:
Plays a role in mitotic exit and cytokinesis. Not required for microtubule nucleation. Recruits PDCD6IP and TSG101 to midbody during cytokinesis.

Subunit:
Homodimer. Interacts (phosphorylated on Ser-425 and Ser-428) with PLK1. Interacts with AKAP9; the interaction occurs in interphase and is lost upon mitotic entry. Interacts with PCNT; the interaction occurs in interphase and is lost upon mitotic entry. Interacts with PDCD6IP; the interaction is direct; CEP55 binds PDCD6IP in a 2:1 stoechiometry; PDCD6IP competes with TSG101 for the same binding site. Interacts with TSG101; TSG101 competes with PDCD6IP for the same binding site; interaction is required for cytokinesis but not for viral budding. Interacts with MVB12A, VPS37B, VPS37C and VPS28.

Subcellular Location:
Cytoplasm, cytoskeleton, centrosome, centriole. Cytoplasm, cytoskeleton, centrosome. Cleavage furrow. Midbody. Note=Present at the centrosomes at interphase. A small portion is associated preferentially with the mother centriole, whereas the majority localizes to the pericentriolar material. During mitosis, loss of affinity for the centrosome at the onset of prophase and diffusion throughout the cell. This dissociation from the centrosome is phosphorylation-dependent. May remain localized at the centrosome during mitosis in certain cell types. Appears at the cleavage furrow in late anaphase and in the midbody in cytokinesis.

Tissue Specificity:
Widely expressed, mostly in proliferative tissues. Highly expressed in testis. Intermediate levels in adult and fetal thymus, as well as in various cancer cell lines. Low levels in different parts of the digestive tract, bone marrow, lymph nodes, placenta, fetal heart and fetal spleen. Hardly detected in brain.

Post-translational modifications:
There is a hierachy of phosphorylation, where both Ser-425 and Ser-428 are phosphorylated at the onset of mitosis, prior to Ser-436. Phosphorylation at Ser-425 and Ser-428 is required for dissociation from the centrosome at the G2/M boundary. Phosphorylation at the 3 sites, Ser-425, Ser-428 and Ser-436, is required for protein function at the final stages of cell division to complete cytokinesis successfully.

Database links:

Entrez Gene: 55165 Human

Entrez Gene: 74107 Mouse

Entrez Gene: 294074 Rat

Omim: 610000 Human

SwissProt: Q53EZ4 Human

SwissProt: Q8BT07 Mouse

SwissProt: Q4V7C8 Rat

Unigene: 14559 Human

Unigene: 9916 Mouse

Unigene: 90818 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 亚洲精品18 | 亚洲欧美精选 | 色噜噜亚洲男人的天堂 | 国产亚洲精品久久久一区 | 欧美日本中文 | 激情另类小说区图片区视频区 | 少妇在宾馆高潮不断狂叫床 | 男生插女生的网站 | 欧美色图bt | 免费观看18禁无遮挡真人网站 | 久久99精品国产麻豆婷婷小说 | 欧美精品一区二区三区久久狼 | 亚洲亚洲人成综合丝袜图片 | 日本人在线观看 | 国产精品视频1区2区3区 | 亚洲国产日韩a综合在线 | 欧美一级免费高清 | 亚韩精品 | wwwwwww黄| 风韵丰满熟妇啪啪区老老熟女百度 | 国产91精品精华液一区二区三区 | 亚洲国产网址 | 在线看片无码永久免费AV | 亚洲乱码一二三四区 | 少妇宾馆把腿扒开让我添 | 2023国精产品一二二线免费 | 91免费高清观看 | 18禁无遮挡免费视频网站 | 久久97视频| 日韩99 | 蜜臀av免费一区二区三区久久乐 | 美女视频三区 | 免费性av| 亚洲久久中文字幕 | 一区av在线| 欧美视频精品 | 亚洲欧洲日本无在线码天堂 | 国产一卡2卡3卡4卡新区乱码在 | 成人午夜做爰视频免费看 | 久草老司机 | 激情亚洲AV无码日韩色 |