97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
青青青国产精品视频,国产性生活免费视频,欧美末成年video水多
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-CEP55/PE-Cy5.5 Conjugated antibody (bs-7742R-PE-Cy5.5)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-7742R-PE-Cy5.5
英文名稱 Rabbit Anti-CEP55/PE-Cy5.5 Conjugated antibody
中文名稱 PE-Cy5.5標記的中心體蛋白55kDa抗體
別    名 C10orf3; Centrosomal protein 55kDa; Centrosomal protein of 55 kDa; CEP 55; FLJ10540; Up regulated in colon cancer 6; URCC 6; URCC6; CEP55_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  細胞周期蛋白  細胞分化  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse,  (predicted: Human, Rat, Dog, Pig, Horse, Sheep, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 54kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CEP55
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
CEP55 (Centrosomal protein 55kDa) is essential for mitotic exit and cytokinesis. It is not required for microtubule nucleation.

Function:
Plays a role in mitotic exit and cytokinesis. Not required for microtubule nucleation. Recruits PDCD6IP and TSG101 to midbody during cytokinesis.

Subunit:
Homodimer. Interacts (phosphorylated on Ser-425 and Ser-428) with PLK1. Interacts with AKAP9; the interaction occurs in interphase and is lost upon mitotic entry. Interacts with PCNT; the interaction occurs in interphase and is lost upon mitotic entry. Interacts with PDCD6IP; the interaction is direct; CEP55 binds PDCD6IP in a 2:1 stoechiometry; PDCD6IP competes with TSG101 for the same binding site. Interacts with TSG101; TSG101 competes with PDCD6IP for the same binding site; interaction is required for cytokinesis but not for viral budding. Interacts with MVB12A, VPS37B, VPS37C and VPS28.

Subcellular Location:
Cytoplasm, cytoskeleton, centrosome, centriole. Cytoplasm, cytoskeleton, centrosome. Cleavage furrow. Midbody. Note=Present at the centrosomes at interphase. A small portion is associated preferentially with the mother centriole, whereas the majority localizes to the pericentriolar material. During mitosis, loss of affinity for the centrosome at the onset of prophase and diffusion throughout the cell. This dissociation from the centrosome is phosphorylation-dependent. May remain localized at the centrosome during mitosis in certain cell types. Appears at the cleavage furrow in late anaphase and in the midbody in cytokinesis.

Tissue Specificity:
Widely expressed, mostly in proliferative tissues. Highly expressed in testis. Intermediate levels in adult and fetal thymus, as well as in various cancer cell lines. Low levels in different parts of the digestive tract, bone marrow, lymph nodes, placenta, fetal heart and fetal spleen. Hardly detected in brain.

Post-translational modifications:
There is a hierachy of phosphorylation, where both Ser-425 and Ser-428 are phosphorylated at the onset of mitosis, prior to Ser-436. Phosphorylation at Ser-425 and Ser-428 is required for dissociation from the centrosome at the G2/M boundary. Phosphorylation at the 3 sites, Ser-425, Ser-428 and Ser-436, is required for protein function at the final stages of cell division to complete cytokinesis successfully.

Database links:

Entrez Gene: 55165 Human

Entrez Gene: 74107 Mouse

Entrez Gene: 294074 Rat

Omim: 610000 Human

SwissProt: Q53EZ4 Human

SwissProt: Q8BT07 Mouse

SwissProt: Q4V7C8 Rat

Unigene: 14559 Human

Unigene: 9916 Mouse

Unigene: 90818 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 91精品国产综合久久久久久蜜月 | 91爱爱·com | 亚洲一区二区视频在线观看 | 国产成在线观看免费视频成本人 | 亚洲成AV人影院在线观看网 | 久久av资源 | 激情另类小说区图片区视频区 | 阿公抱着我边摸边吃奶视频 | 在线观看国产中文字幕 | 逼自拍偷拍自拍天堂偷拍 | www.精品一区 | 日本拍拍免费观看片成人 | 一本久道综合在线中文无码 | 久久久国语 | 少妇人妻陈艳和黑人教练 | 国产欧美亚洲精品 | 中文字幕亚洲一区一区 | 久久精品免费看 | 一线天逼逼 | aaa级精品久久久国产片 | 亚洲国产成人爱av在线播放 | 饕餮记在线观看 | 37人体做爰久久久久久 | 中日韩一区二区 | 无码性按摩AV在线观看 | 91看大片 | 一区二区三区四区视频免费观看 | 伊人久久成人网 | 国产在线观看第一页 | 国产在线一二三四区 | 成在人线AV无码免费高潮喷水 | 亚洲手机av| 日本伦理片在线播放 | 日韩中字在线 | 免费一区二区三区在线观看 | 国产成人综合激情视频在线观看 | 一本大道香蕉久在线播放29 | 日本深夜福利 | 精品永久久福利一区二区 | 3d动漫足控福利动漫合集 | 人成在线免费网站 |