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Rabbit Anti-SEPT1/BF647 Conjugated antibody (bs-7769R-BF647)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-7769R-BF647
英文名稱 Rabbit Anti-SEPT1/BF647 Conjugated antibody
中文名稱 BF647標記的細胞分化蛋白SEP1抗體
別    名 DIFF6; Differentiation 6 (deoxyguanosine triphosphate triphosphohydrolase); LARP; Peanut like protein 3; PNUTL3; SEP1; Septin 1; Septin1; Serologically defined breast cancer antigen NY BR 24; SEPT1_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  神經生物學  信號轉導  細胞周期蛋白  細胞分化  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 40kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SEPT1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
SEPT1 is a member of the septin family of GTPases. Members of this family are required for cytokinesis. SEPT1 is associated with the tau-based paired helical filament core, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease.

Function:
Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential).

Subunit:
Septins polymerize into heterooligomeric protein complexes that form filaments, and can associate with cellular membranes, actin filaments and microtubules. GTPase activity is required for filament formation (By similarity). Interacts with AURKB.

Subcellular Location:
Cytoplasm. Cytoplasm, cytoskeleton.

Tissue Specificity:
Expressed at high levels in lymphoid and haematopoietic tissues.

Similarity:
Belongs to the septin family.

Database links:

Entrez Gene: 1731 Human

Entrez Gene: 54204 Mouse

Entrez Gene: 293507 Rat

Omim: 612897 Human

SwissProt: Q8WYJ6 Human

SwissProt: P42209 Mouse

SwissProt: Q5EB96 Rat

Unigene: 632176 Human

Unigene: 18 Mouse

Unigene: 68675 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

SEPTIN(SEPT)家族是細胞骨架蛋白的一種,具有GTPase的活性。經研究發現,SEPT參與細胞核分裂、細胞膜的運輸以及構成細胞骨架。
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