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Rabbit Anti-GLP2R/PE Conjugated antibody (bs-7800R-PE)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-7800R-PE
英文名稱 Rabbit Anti-GLP2R/PE Conjugated antibody
中文名稱 PE標記的胰高血糖素樣肽2受體抗體
別    名 GLP 2 R; GLP 2 receptor; GLP 2R; GLP-2 receptor; GLP-2-R; GLP-2R; GLP2 R; GLP2 Receptor; GLP2R; GLP2R_HUMAN; Glucagon Like Peptide 2 Receptor; Glucagon-like peptide 2 receptor.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  信號轉導  細胞周期蛋白  G蛋白偶聯受體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Dog, Pig, Cow, Horse, Rabbit, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 63kDa
細胞定位 細胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GLP2R
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
The GLP2 receptor (GLP2R) is a G protein-coupled receptor superfamily member closely related to the glucagon receptor ans GLP1 receptor. Glucagon-like peptide-2 (GLP2) is a 33-amino acid proglucagon-derived peptide produced by intestinal enteroendocrine cells. Like glucagon-like peptide-1 (GLP1) and glucagon itself, it is derived from the proglucagon peptide encoded by the GCG gene. GLP2 stimulates intestinal growth and upregulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. Moreover, GLP2 prevents intestinal hypoplasia resulting from total parenteral nutrition. GLP2R, a G protein-coupled receptor superfamily member is expressed in the gut and closely related to the glucagon receptor (GCGR) and the receptor for GLP1 (GLP1R). [provided by RefSeq, Jul 2008].

Function:
This is a receptor for glucagon-like peptide 2. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Similarity:
Belongs to the G-protein coupled receptor 2 family.

Database links:

Entrez Gene: 511942 Cow

Entrez Gene: 101137449 Gorilla

Entrez Gene: 9340 Human

Entrez Gene: 101032630 Monkey

Entrez Gene: 100515966 Pig

Omim: 603659 Human

SwissProt: O95838 Human

Unigene: 248202 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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