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Rabbit Anti-RABGAP1/BF488 Conjugated antibody (bs-7826R-BF488)
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訂購(gòu)QQ:  400-901-9800
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-7826R-BF488
英文名稱 Rabbit Anti-RABGAP1/BF488 Conjugated antibody
中文名稱 BF488標(biāo)記的Rab蛋白GTP酶激活蛋白1抗體
別    名 Rab GTPase-activating protein 1; Rab GAP1, GAP and centrosome associated protein; HSPC094; Rab GTPase activating protein 1; Rab6 GTPase activating protein GAPCenA; RBGP1_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞周期蛋白  細(xì)胞類型標(biāo)志物  G蛋白信號(hào)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Sheep, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 122kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RABGAP1
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Rab GTPase-activating protein 1 is a 1,069 amino acid cytoplasmic protein containing one PID domain and one Rab-GAP TBC domain. Rab GAP1 acts as a GTPase-activating protein of Rab 6A in the Rab 6A-mediated pathway, which is involved in the metaphase-anaphase transition. Expressed as four alternatively spliced variants, Rab GAP1 may also be involved in the microtubule nucleation by centrosome and in Golgi dynamics during the cell cycle. Rab GAP1 is encoded by a gene located on human chromosome 9, which consists of about 145 million bases, 4% of the human genome and encodes nearly 900 genes.

Function:
May act as a GTPase-activating protein of RAB6A. Mayplay a role in microtubule nucleation by centrosome. Mayparticipate in a RAB6A-mediated pathway involved in themetaphase-anaphase transition.

Subunit:
Interacts with RAB6A and tubulin gamma.

Subcellular Location:
Cytoplasm, cytosol. Cytoplasm, cytoskeleton,centrosome. Note=Predominantly cytosolic but also associated withthe centrosome.

Similarity:
Contains 1 PID domain.
Contains 1 Rab-GAP TBC domain.

Database links:

Entrez Gene: 519260 Cow

Entrez Gene: 23637 Human

Entrez Gene: 227800 Mouse

Entrez Gene: 311911 Rat

SwissProt: Q9Y3P9 Human

SwissProt: A2AWA9 Mouse

Unigene: 271341 Human

Unigene: 383192 Mouse

Unigene: 14944 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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