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Rabbit Anti-RABGAP1/BF594 Conjugated antibody (bs-7826R-BF594)
訂購熱線:400-901-9800
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-7826R-BF594
英文名稱 Rabbit Anti-RABGAP1/BF594 Conjugated antibody
中文名稱 BF594標記的Rab蛋白GTP酶激活蛋白1抗體
別    名 Rab GTPase-activating protein 1; Rab GAP1, GAP and centrosome associated protein; HSPC094; Rab GTPase activating protein 1; Rab6 GTPase activating protein GAPCenA; RBGP1_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  信號轉導  細胞周期蛋白  細胞類型標志物  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 122kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RABGAP1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Rab GTPase-activating protein 1 is a 1,069 amino acid cytoplasmic protein containing one PID domain and one Rab-GAP TBC domain. Rab GAP1 acts as a GTPase-activating protein of Rab 6A in the Rab 6A-mediated pathway, which is involved in the metaphase-anaphase transition. Expressed as four alternatively spliced variants, Rab GAP1 may also be involved in the microtubule nucleation by centrosome and in Golgi dynamics during the cell cycle. Rab GAP1 is encoded by a gene located on human chromosome 9, which consists of about 145 million bases, 4% of the human genome and encodes nearly 900 genes.

Function:
May act as a GTPase-activating protein of RAB6A. Mayplay a role in microtubule nucleation by centrosome. Mayparticipate in a RAB6A-mediated pathway involved in themetaphase-anaphase transition.

Subunit:
Interacts with RAB6A and tubulin gamma.

Subcellular Location:
Cytoplasm, cytosol. Cytoplasm, cytoskeleton,centrosome. Note=Predominantly cytosolic but also associated withthe centrosome.

Similarity:
Contains 1 PID domain.
Contains 1 Rab-GAP TBC domain.

Database links:

Entrez Gene: 519260 Cow

Entrez Gene: 23637 Human

Entrez Gene: 227800 Mouse

Entrez Gene: 311911 Rat

SwissProt: Q9Y3P9 Human

SwissProt: A2AWA9 Mouse

Unigene: 271341 Human

Unigene: 383192 Mouse

Unigene: 14944 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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