97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
91嫩草私人成人亚洲影院,美女一区二区在线观看,欧美高清精品videosexold
Rabbit Anti-SKA2/Biotin Conjugated antibody (bs-7847R-Bio)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說(shuō) 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-7847R-Bio
英文名稱 Rabbit Anti-SKA2/Biotin Conjugated antibody
中文名稱 生物素標(biāo)記的紡錘體和著絲粒相關(guān)蛋白2抗體
別    名 FAM33A; Family with sequence similarity 33, member A; FLJ12758; MGC110975; Protein FAM33A; SKA 2; SKA2; SKA2_HUMAN; Spindle and kinetochore associated complex subunit 2; Spindle and kinetochore associated protein 2; Spindle and kinetochore-associated protein 2; Spindle and KT (kinetochore) associated 2; Spindle and KT associated 2.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  細(xì)胞周期蛋白  細(xì)胞分化  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, )
產(chǎn)品應(yīng)用 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 14kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SKA2
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Ska2 (spindle and kinetochore associated complex subunit 2), also known as FAM33A, is a 121 amino acid component of the Ska1 complex, a microtubule-binding subcomplex of the outer kinetochore that is critical for proper chromosome segregation. The Ska1 complex is a component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. Localized to the outer kinetochore and spindle microtubules during cell proliferation, Ska2 is essential for spindle checkpoint silencing and exit from mitosis. Downregulation of Ska2 leads to delayed recruitment of MAD2, a component of the mitotic spindle checkpoint, to several kinetochores resulting in occasional loss of individual chromosomes from the metaphase plate. Ska2 is encoded by a gene located on human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes.

Function:
Component of the SKA1 complex, a microtubule-bindingsubcomplex of the outer kinetochore that is essential for properchromosome segregation. Required for timely anaphase onset duringmitosis, when chromosomes undergo bipolar attachment on spindlemicrotubules leading to silencing of the spindle checkpoint. TheSKA1 complex is a direct component of the kinetochore-microtubuleinterface and directly associates with microtubules as oligomericassemblies. The complex facilitates the processive movement ofmicrospheres along a microtubule in a depolymerization-coupledmanner. In the complex, it is required for SKA1 localization.

Subunit:
Component of the SKA1 complex, composed of SKA1, SKA2 andSKA3. Forms a heterodimer with SKA1; the heterodimer interactingwith SKA3. The core SKA1 complex is composed of 2 SKA1-SKA2heterodimers, each heterodimer interacting with a molecule of theSKA3 homodimer. The core SKA1 complex associates with microtubulesand forms oligomeric assemblies. Interacts directly with SKA1.Binds directly to microtubules; but with a much lower affinity thanSKA1. May interact with NR3C1; the relevance of such interactionremains unclear in vivo.

Subcellular Location:
Cytoplasm, cytoskeleton, spindle.Chromosome, centromere, kinetochore. Note=Localizes to the outerkinetochore and spindle microtubules during mitosis in a NDC80complex-dependent manner. Localizes to both the mitotic spindle andkinetochore-associated proteins.

Similarity:
Belongs to the SKA2 family.

Database links:

Entrez Gene: 348235 Human

Entrez Gene: 66140 Mouse

Entrez Gene: 287598 Rat

Entrez Gene: 691962 Rat

SwissProt: Q8WVK7 Human

SwissProt: Q9CR46 Mouse

SwissProt: Q5I0J4 Rat

Unigene: 463607 Human

Unigene: 45008 Mouse

Unigene: 203397 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.kastlife.cn 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
主站蜘蛛池模板: 亚洲欧洲老熟女AV | 大陆熟女丰满XXXXX富婆 | 99精品黄色 | 午夜精品久久久久9999高清 | 亚洲中文无码成人手机版 | 国产大陆亚洲精品国产 | 成人高清在线 | 晚上偷偷与邻居做爰了小说 | 美女操av | 国产各种高潮合集在线观看 | www.com在线观看 | 野花社区www官网在线观看 | 大地资源二在线观看官网 | 日韩一级黄 | japanese在线看| 亚洲欧美日韩专区 | 久久久久无| 久久精品国产亚洲av高那 | 久久精品视频在线观看 | 精品日本一区二区三区免费 | 一区av在线| 国产三级久久久 | www.com在线观看 | 在线观看亚洲欧美视频免费 | 欧美黑人肉体狂欢大派对 | 精品熟女碰碰人人A久久 | 91一区二区三区四区 | 精品国产一区二区三区久久狼5月 | 亚洲一区天堂 | 亚洲欧美日韩自偷自拍 | 蜜桃久久精品乱码一区二区 | 扒开双腿猛进入喷水高潮视频 | 国产美女精品福利一区二区 | 色婷婷五月综合激情中文字幕 | 精品无码日韩一区二区三区不卡 | 中文一区二区三区四区 | 亚洲AV永久无码AV激情A片 | 人人超碰人人爱超碰国产 | 中文字幕在线观看欧美 | 国产一级一片免费播放 | 日韩福利二区 |