97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
成人黄网站片免费视频,一级免费黄视频,国产乱妇4p交换乱免费视频
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-SKA2/PE-Cy3 Conjugated antibody (bs-7847R-PE-Cy3)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-7847R-PE-Cy3
英文名稱 Rabbit Anti-SKA2/PE-Cy3 Conjugated antibody
中文名稱 PE-Cy3標記的紡錘體和著絲粒相關蛋白2抗體
別    名 FAM33A; Family with sequence similarity 33, member A; FLJ12758; MGC110975; Protein FAM33A; SKA 2; SKA2; SKA2_HUMAN; Spindle and kinetochore associated complex subunit 2; Spindle and kinetochore associated protein 2; Spindle and kinetochore-associated protein 2; Spindle and KT (kinetochore) associated 2; Spindle and KT associated 2.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  細胞周期蛋白  細胞分化  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 14kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SKA2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Ska2 (spindle and kinetochore associated complex subunit 2), also known as FAM33A, is a 121 amino acid component of the Ska1 complex, a microtubule-binding subcomplex of the outer kinetochore that is critical for proper chromosome segregation. The Ska1 complex is a component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. Localized to the outer kinetochore and spindle microtubules during cell proliferation, Ska2 is essential for spindle checkpoint silencing and exit from mitosis. Downregulation of Ska2 leads to delayed recruitment of MAD2, a component of the mitotic spindle checkpoint, to several kinetochores resulting in occasional loss of individual chromosomes from the metaphase plate. Ska2 is encoded by a gene located on human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes.

Function:
Component of the SKA1 complex, a microtubule-bindingsubcomplex of the outer kinetochore that is essential for properchromosome segregation. Required for timely anaphase onset duringmitosis, when chromosomes undergo bipolar attachment on spindlemicrotubules leading to silencing of the spindle checkpoint. TheSKA1 complex is a direct component of the kinetochore-microtubuleinterface and directly associates with microtubules as oligomericassemblies. The complex facilitates the processive movement ofmicrospheres along a microtubule in a depolymerization-coupledmanner. In the complex, it is required for SKA1 localization.

Subunit:
Component of the SKA1 complex, composed of SKA1, SKA2 andSKA3. Forms a heterodimer with SKA1; the heterodimer interactingwith SKA3. The core SKA1 complex is composed of 2 SKA1-SKA2heterodimers, each heterodimer interacting with a molecule of theSKA3 homodimer. The core SKA1 complex associates with microtubulesand forms oligomeric assemblies. Interacts directly with SKA1.Binds directly to microtubules; but with a much lower affinity thanSKA1. May interact with NR3C1; the relevance of such interactionremains unclear in vivo.

Subcellular Location:
Cytoplasm, cytoskeleton, spindle.Chromosome, centromere, kinetochore. Note=Localizes to the outerkinetochore and spindle microtubules during mitosis in a NDC80complex-dependent manner. Localizes to both the mitotic spindle andkinetochore-associated proteins.

Similarity:
Belongs to the SKA2 family.

Database links:

Entrez Gene: 348235 Human

Entrez Gene: 66140 Mouse

Entrez Gene: 287598 Rat

Entrez Gene: 691962 Rat

SwissProt: Q8WVK7 Human

SwissProt: Q9CR46 Mouse

SwissProt: Q5I0J4 Rat

Unigene: 463607 Human

Unigene: 45008 Mouse

Unigene: 203397 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 久久性av | 免费v片在线观看 | 中文日产幕无线码一区2023 | 我要看免费毛片 | 日韩黄色大片在线观看 | 久久久久人妻精品区一三寸 | 国产人妻高清国产拍精品 | 午夜福利无码不卡在线观看 | 亚洲最大成人 | 国内毛片久久 | 91精品一区二区三区在线观看 | 人妻无码中文久久久久专区 | 欧美交换配乱吟粗大 | 99在线成人精品视频 | 国产99久久亚洲综合精品西瓜tv | 夜夜操天天干 | 久久精品中文骚妇内射AV | 欧美va免费高清在线观看 | 久久久久久久波多野结衣高潮 | 精品久久久久久一区二区里番 | 久久精品国产亚洲aⅴ瑜伽 操处女逼小说 | 色两性网欧美 | 精品在线观看一区二区 | 亚洲国产成人精品女人久久久久 | 美女高潮无遮挡喷水视频 | 秋霞午夜av一区二区三区 | 欧美《熟妇的荡欲》在线观看 | 伊人狠狠色j香婷婷综合 | 亚洲日本成本人观看 | 成人黄色免费观看 | 欧美生活1级 | 国产亚洲精品一区二555 | 国产精品无码一区二区三区不卡 | 大陆熟女丰满XXXXX富婆 | 最近日本mv字幕免费高清在线 | 国产精品无码dvd在线观看 | 免费无码又爽又刺激高潮视频 | 热久久性 | 久久久日韩精品一区二区 | 西西最大胆日本无码视频 | 伊人精品成人久久综合软件 |