97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
手机在线看永久AV片免费,国产熟睡乱子伦视频,婷婷综合网入口
Rabbit Anti-SUPT16H/RBITC Conjugated antibody (bs-7879R-RBITC)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-7879R-RBITC
英文名稱 Rabbit Anti-SUPT16H/RBITC Conjugated antibody
中文名稱 羅丹明(RBITC)標(biāo)記的染色體特異性轉(zhuǎn)錄延伸因子抗體
別    名 CDC68; Chromatin specific transcription elongation factor 140 kDa subunit; Chromatin-specific transcription elongation factor 140 kDa subunit; Facilitates chromatin transcription complex subunit SPT16; FACT 140 kDa subunit; FACT; FACT complex subunit SPT16; FACTP140; FLJ10857; FLJ14010; hSPT16; SP16H_HUMAN; Suppressor of Ty 16 homolog; Supt16h.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  信號轉(zhuǎn)導(dǎo)  細(xì)胞周期蛋白  轉(zhuǎn)錄調(diào)節(jié)因子  細(xì)胞分化  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse,  (predicted: Human, Rat, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 120kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SUPT16H/CDC68
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II. The FACT complex is probably also involved in phosphorylation of 'Ser-392' of p53/TP53 via its association with CK2 (casein kinase II). Also involved in vitamin D-coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene.

Function:
Component of the FACT complex, a general chromatinfactor that acts to reorganize nucleosomes. The FACT complex isinvolved in multiple processes that require DNA as a template suchas mRNA elongation, DNA replication and DNA repair. Duringtranscription elongation the FACT complex acts as a histonechaperone that both destabilizes and restores nucleosomalstructure. It facilitates the passage of RNA polymerase II andtranscription by promoting the dissociation of one histone H2A-H2Bdimer from the nucleosome, then subsequently promotes thereestablishment of the nucleosome following the passage of RNApolymerase II. The FACT complex is probably also involved inphosphorylation of 'Ser-392' of p53/TP53 via its association withCK2 (casein kinase II). Also involved in vitamin D-coupledtranscription regulation via its association with the WINACcomplex, a chromatin-remodeling complex recruited by vitamin Dreceptor (VDR), which is required for the ligand-bound VDR-mediatedtransrepression of the CYP27B1 gene (By similarity).

Subunit:
Component of the FACT complex, a stable heterodimer ofSSRP1 and SUPT16H. Also component of a CK2-SPT16-SSRP1 complexwhich forms following UV irradiation, composed of SSRP1, SUPT16H,CSNK2A1, CSNK2A2 and CSNK2B. Component of the WINAC complex, atleast composed of SMARCA2, SMARCA4, SMARCB1, SMARCC1, SMARCC2,SMARCD1, SMARCE1, ACTL6A, BAZ1B/WSTF, ARID1A, SUPT16H, CHAF1A andTOP2B. Interacts with NEK9. Binds to histone H2A-H2B. Interactswith GTF2E2.

Subcellular Location:
Nucleus. Chromosome. Note=Colocalizes withRNA polymerase II on chromatin. Recruited to actively transcribedloci.

Tissue Specificity:
Ubiquitous.

Post-translational modifications:
ADP-ribosylated. ADP-ribosylation by PARP1 is induced bygenotoxic stress and correlates with dissociation of FACT fromchromatin.

Similarity:
Belongs to the peptidase M24 family. SPT16 subfamily.

Database links:

Entrez Gene: 514989 Cow

Entrez Gene: 612874 Dog

Entrez Gene: 11198 Human

Entrez Gene: 114741 Mouse

Entrez Gene: 305851 Rat

Omim: 605012 Human

SwissProt: E1BNP8 Cow

SwissProt: Q9Y5B9 Human

SwissProt: Q920B9 Mouse

Unigene: 213724 Human

Unigene: 21662 Mouse

Unigene: 93187 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.kastlife.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
主站蜘蛛池模板: 色老板精品视频在线观看 | 岛国毛片 | 女人15一17毛片 | 日本伊人精品一区二区三区观看方式 | 久久久久亚洲AV成人片无码 | 99久久久久免费精品国产 | 日本三级午夜在线看激 | 日韩一区二区三区四区在线 | 俺也来俺也去天天综合久久 | 午夜嘿嘿| 性一交一乱一伦一色一情孩交 | 色欲狠狠躁天天躁无码中文字幕 | 亚洲第一区久久 | 亚洲国产网址 | 欧美综合一区二区 | 国产精品久久不射 | 久久青草免费视频 | 九九九九色 | 正在播放国产对白孕妇作爱 | 国产精品香蕉在线观看网 | 中文字幕高清在线 | 免费网站看v片在线a | 九九一级片 | 精品无吗乱吗av国产爱色 | 国产精品无码无卡在线观看久 | 精品国产伦一区二区三区 | 亚洲AV无码国产精品色 | 免费一区区三区四区 | 一本大道专区 | 成人福利国产精品视频 | 亚洲手机在线播放 | 久久久久久久久久久久久久久国产 | 国产美女精品视频线免费播放软件 | 黄色动态图视频 | 欧美黑人狂躁日本寡妇 | 精品毛片 | 亚洲双插 | 色香蕉在线 | 久久天堂av综合色无码专区 | 免费av免费看 | 正在播放露脸一区 |