97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
有色金属网长江现货,91久久精品国产一区二区三区,亚欧毛片
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-RIT1/FITC Conjugated antibody (bs-8392R-FITC)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-8392R-FITC
英文名稱 Rabbit Anti-RIT1/FITC Conjugated antibody
中文名稱 FITC標記的RIT1蛋白抗體
別    名 GTP binding protein Roc1; GTP-binding protein Rit1; Ras like protein expressed in many tissues; Ras like without CAAX 1; Ras-like protein expressed in many tissues; Ras-like without CAAX protein 1; RIBB; Ric like expressed in many tissues; RIT; RIT1; RIT1_HUMAN; ROC1.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  免疫學  神經生物學  信號轉導  G蛋白偶聯受體  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 25kDa
細胞定位 細胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RIT1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Plays a crucial role in coupling NGF stimulation to the activation of both EPHB2 and MAPK14 signaling pathways and in NGF-dependent neuronal differentiation.
Neuronal activity dramatically increases the concentration of cytosolic Ca2+, which then serves as a second messenger to direct diverse cellular responses. Calmodulin is a primary mediator of Ca2+ signals in the nervous system. Ric, a protein related to the Ras subfamily of small GTPases, has the ability to bind calmodulin. In addition, two Ras-like human proteins, Rin and Rit (Ric-related gene expressed in many tissues), which are 71% and 66% identical to RIC respectively, share related G2 domains with Ric. While most members of the Ras subfamily are plasma membrane-associated and generally require a C-terminal isoprenyl group to bind to the plasma membrane, Rit and Rin lack the recognition signal for C-terminal prenylation. Transiently expressed Rit and Rin are plasma membrane-localized because both proteins contain a C-terminal cluster of basic amino acids, which provides a mechanism for membrane association. Rin binds calmodulin through a C-terminal binding motif. Rit and Ric are widely expressed, whereas expression of Rin is restricted to the neuron system. In conclusion, Rit and Rin define a novel subfamily of Ras-related proteins

Function:
Plays a crucial role in coupling NGF stimulation to the activation of both EPHB2 and MAPK14 signaling pathways and in NGF-dependent neuronal differentiation.

Subunit:
Interacts with MLLT4, the C-terminal domain of RALGDS and RLF, but not with RIN1 and PIK3CA. RLF binds exclusively to the active GTP-bound form. Strongly interacts with BRAF, but only weakly with RAF1. BARF and RAF1 association is dependent upon the GTP-bound state. Interacts with RGL3 (By similarity).

Subcellular Location:
Cell membrane.

Tissue Specificity:
Expressed in many tissues.

Similarity:
Belongs to the small GTPase superfamily. Ras family.

Database links:
UniProtKB/Swiss-Prot: Q92963.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 免费看国产一级特黄aaaa大片 | 久久AV无码乱码A片无码 | 伦理片一区二区三区 | 99久热RE在线精品99RE6 | 中文字幕第36页 | 亚洲美女久久 | 永久黄网站色视频免费 | 国产一级大毛片 | 成人免费看吃奶视频网站 | 沦为公交两奶头春药高潮迭起 | 2019中文字幕久久 | 国产丝袜美女一区二区三区 | 人妻丰满熟妇无码区免费 | 欧美成人看片一区二区三区尤物 | 嫩草院一区二区乱码蜜臀 | 免费黄网在线 | 毛片一级免费看 | 白天躁晚上躁麻豆视频 | 精品国产一区二区三区久久狼5月 | 亚洲一区二区精品视频 | 秋霞无码一区二区视频在线观看 | 成人精品在线视频 | 国产女人高潮叫床视频 | 在线观看成人高清a | 免费三级国产 | 久久精品福利 | 日韩一区二区观看 | 黄色毛片一级视频 | 中国精品视频久久久久久 | 99午夜| GOGOGO免费高清视频3 | 高清国产一区二区三区在线 | 日本少妇激三级做爰在线 | 一本大道无码人妻精品专区 | 午夜久操| 日韩国产精品91 | 欧美性开放情侣网站 | 在线看福利中文字幕人妻 | 国产精品久久久久无码 | 久久精品欧美视频 | 色综合欧美|