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Rabbit Anti-CDX2+3/Biotin Conjugated antibody (bs-9236R-Bio)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-9236R-Bio
英文名稱 Rabbit Anti-CDX2+3/Biotin Conjugated antibody
中文名稱 生物素標記的尾側型同源轉錄因子2/3抗體
別    名 Caudal type homeo box 2; Caudal type homeo box transcription factor 2; Caudal type homeobox 2; Caudal type homeobox protein 2; caudal type homeobox transcription factor 2; Caudal-type homeobox protein 2; CDX 2; CDX 3; CDX-3; Cdx2; CDX2_HUMAN; CDX3; CDX2+3; Homeobox protein CDX 2; Homeobox protein CDX-2.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  發育生物學  信號轉導  干細胞  轉錄調節因子  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Pig, Cow, Horse, )
產品應用 WB=1:50-200 ELISA=1:100-1000 IHC-F=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 34kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CDX2/3
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded protein is a major regulator of intestine-specific genes involved in cell growth an differentiation. This protein also plays a role in early embryonic development of the intestinal tract. Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis. [provided by RefSeq, Jan 2012].

Function:
Involved in the transcriptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine.

Subcellular Location:
Nucleus.

Post-translational modifications:
Phosphorylation of Ser-60 mediates the transactivation capacity.

Similarity:
Belongs to the Caudal homeobox family.
Contains 1 homeobox DNA-binding domain.

Database links:

Entrez Gene: 1045 Human

Entrez Gene: 12591 Mouse

Entrez Gene: 66019 Rat

Omim: 600297 Human

SwissProt: Q99626 Human

SwissProt: P43241 Mouse

Unigene: 174249 Human

Unigene: 20358 Mouse

Unigene: 64495 Ra



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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