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Rabbit Anti-CT135/ODF3/Gold Conjugated antibody (bs-9406R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產品編號 bs-9406R-Gold
英文名稱 Rabbit Anti-CT135/ODF3/Gold Conjugated antibody
中文名稱 膠體金標記的腫瘤/睪丸抗原135抗體
別    名 Cancer/testis antigen 135; CT135; hSHIPPO; odf3; ODF3A_HUMAN; Outer dense fiber of sperm tails 3; Outer dense fiber of sperm tails protein 3; Outer dense fiber protein 3; SHIPPO1; Sperm tail protein SHIPPO 1; Sperm tail protein SHIPPO1; TISP50; Transcript induced in spermiogenesis protein 50.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 腫瘤  細胞生物  發育生物學  細胞周期蛋白  細胞分化  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, )
產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 28kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ODF3/CT135
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產品介紹 background:
Outer dense fibers are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail. May help to maintain the passive elastic structures and elastic recoil of the sperm tail.
Constituting the main cytoskeletal structure of spermatid flagella, outer dense fibers (ODFs) add elastic recoil, stiffness and protection against shear forces during sperm movement. Human ODFs consist of approximately 10 major and at least 15 minor proteins. The major proteins of the ODF include Odf1, Odf2, and Odf3, which compose a family of proteins that are preferentially expressed during mammalian spermiogenesis. Odf3 (outer dense fiber protein 3), also known as sperm tail protein SHIPPO 1 and TISP50 (transcript induced in spermiogenesis protein 50), is a 254 amino acid protein that is expressed during the latter part of spermatogenesis in flagella of elongated spermatids and mature sperm. Odf proteins are directed to their exact subcellular location by Spags, which are characterized as chaperone-like Odf-binding molecules. There are two isoforms of Odf3 that are produced as a result of alternative splicing events.

Function:
Outer dense fibers are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail. May help to maintain the passive elastic structures and elastic recoil of the sperm tail.

Subcellular Location:
Cytoplasm. Expressed in the cytoplasmic lobe of spermatids.

Tissue Specificity:
Testis-specific.

Similarity:
Belongs to the ODF3 family.
Contains 2 STPGR (Sperm-tail PG-rich) repeats.

Database links:

Entrez Gene: 113746 Human

Entrez Gene: 69287 Mouse

Omim: 608356 Human

SwissProt: Q96PU9 Human

SwissProt: Q920N1 Mouse

Unigene: 350949 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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