97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
777米奇色888狠狠俺去啦,av资源站在线观看,天堂亚洲免费视频
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-phospho-TEM8 (Tyr382)/HRP Conjugated antibody (bs-5210R-HRP)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-5210R-HRP
英文名稱 Rabbit Anti-phospho-TEM8 (Tyr382)/HRP Conjugated antibody
中文名稱 辣根過氧化物酶標記的磷酸化腫瘤血管內皮標志物8抗體
別    名 Anthrax toxin receptor 1; Anthrax toxin receptor 1 precursor; ANTXR 1; ANTXR1; ATR; TEM-8; TEM 8; TEM8; Tumor Endothelial Marker 8; Tumor endothelial marker 8 precursor; ANTR1_HUMAN; Anthrax toxin receptor-1; FLJ11298; FLJ21776.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
產品類型 磷酸化抗體 
研究領域 腫瘤  細胞生物  免疫學  信號轉導  血管內皮細胞  腫瘤細胞生物標志物  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Pig, Rabbit, Sheep, )
產品應用 WB=1:500-2000 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 45kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human ANTXR1 around the phosphorylation site of Tyr382
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described. [provided by RefSeq, Oct 2008]

Function:
Plays a role in cell attachment and migration. Interacts with extracellular matrix proteins and with the actin cytoskeleton. Mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. Plays a role in the angiogenic response of cultured umbilical vein endothelial cells.

Subunit:
Interacts with gelatin and type 1 collagen. Interacts with the actin cytoskeleton. Binds to the protective antigen (PA) of Bacillus anthracis. Binding does not occur in the presence of calcium.

Subcellular Location:
Cell membrane; Single-pass type I membrane protein. Cell projection, lamellipodium membrane; Single-pass type I membrane protein. Cell projection, filopodium membrane; Single-pass type I membrane protein. Note=At the membrane of lamellipodia and at the tip of actin-enriched filopodia. Colocalizes with actin at the base of lamellipodia.

Tissue Specificity:
Detected in umbilical vein endothelial cells (at protein level). Highly expressed in tumor endothelial cells.

DISEASE:
Defects in ANTXR1 are associated with susceptibility to hemangioma capillary infantile (HCI) [MIM:602089]. HCI are benign, highly proliferative lesions involving aberrant localized growth of capillary endothelium. They are the most common tumor of infancy, occurring in up to 10% of all births. Hemangiomas tend to appear shortly after birth and show rapid neonatal growth for up to 12 months characterized by endothelial hypercellularity and increased numbers of mast cells. This phase is followed by slow involution at a rate of about 10% per year and replacement by fibrofatty stroma.

Similarity:
Belongs to the ATR family.
Contains 1 VWFA domain.

Database links:

Entrez Gene: 84168 Human

Entrez Gene: 69538 Mouse

Entrez Gene: 362393 Rat

Omim: 606410 Human

SwissProt: Q9H6X2 Human

SwissProt: Q9CZ52 Mouse

SwissProt: Q0PMD2 Rat

Unigene: 165859 Human

Unigene: 232525 Mouse

Unigene: 41192 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

腫瘤血管內皮標志物8是I型跨膜蛋白,是一種腫瘤特異性血管內皮標記蛋白。
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 91视频在线网站 | 亚洲综合色丁香婷婷六月图片 | 久久精品国产亚洲aⅴ瑜伽 操处女逼小说 | 亚洲一二三四在线 | 男同男性xx视频在线观看免费 | www.久久成人 | 91精品国产综合久久久久久蜜月 | 国产精久久久久久 | 奇米777四色成人影视 | 国产一区二区精品在线观看 | 国产麻豆精品精东影业AV网站 | 九九久久精品国产 | 精品一区二区三区日本视频 | 欧美老人与小伙子性生交 | 最新一区二区三区 | 欧美少妇喷潮 | 好爽快点深一点好大 | 18禁黄无遮挡网站免费高清 | 精品国产青草久久久久96 | 国产免费永久在线观看 | 少妇大叫又粗又大太爽A片 heyzo朝桐光一区二区 | 日批毛片 | 午夜在线观看影院 | H无码精品动漫在线观看导航 | 上锁的房间中国版免费 | 欧美熟妇bb| 手机在线观看亚洲 | 日产精品久久久 | 中文字幕第31页 | 免费国产女王调教在线视频 | 国产AV无码精品国产精品 | 伊人久久视频在线 | 午夜无毒不卡 | 91av视频免费在线观看 | 少妇爆乳无码专区网站 | 91亚洲一区精品 | 农村妇女野外毛片免费看 | 亚洲精品综合网 | 欧美精品一二三四区 | 人人爱97 | 在线观看av网 |