97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯(lián)系我們
美女高清毛片,国产导航在线,2019中文字幕视频
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-phospho-Cdc25B (Ser323)/Gold Conjugated antibody (bs-5243R-Gold)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產品編號 bs-5243R-Gold
英文名稱 Rabbit Anti-phospho-Cdc25B (Ser323)/Gold Conjugated antibody
中文名稱 膠體金標記的磷酸化細胞分裂周期蛋白25B抗體
別    名 Cdc25B (Phospho-Ser323); Cdc25B (Phospho-S323); p-Cdc25B (Ser323); p-Cdc25B (S323); Cdc 25B; Cdc25b; Cdc-25b; CDC25HU2; Cdc25m2; Cell division cycle 25 homolog B; Cell division cycle 25B; Cell division cycle 25B isoform 1; Cell division cycle 25B isoform 2; Cell division cycle 25B isoform 3; Cell division cycle 25B isoform 4; Cell division cycle 25B isoform 5; Dual specificity phosphatase Cdc25B; M phase inducer phosphatase 2; M-phase inducer phosphatase 2; MPIP2_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
產品類型 磷酸化抗體 
研究領域 腫瘤  細胞生物  免疫學  細胞周期蛋白  激酶和磷酸酶  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, )
產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 65kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human Cdc25B around the phosphorylation site of Ser323
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產品介紹 background:
CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist. [provided by RefSeq, Jul 2008].

Function:
Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2-dependent manner. Directly dephosphorylates CDK1 and stimulates its kinase activity. The three isoforms seem to have a different level of activity.

Subunit:
Interacts with MAPK14 and 14-3-3 proteins.

Subcellular Location:
Cytoplasm, cytoskeleton, centrosome. Cytoplasm, cytoskeleton, spindle pole.

Post-translational modifications:
Phosphorylated by BRSK1 in vitro. Phosphorylated by CHEK1, which inhibits the activity of this protein. Phosphorylation at Ser-353 by AURKA might locally participate in the control of the onset of mitosis. Phosphorylation by MELK at Ser-169 promotes localization to the centrosome and the spindle poles during mitosis. Phosphorylation at Ser-323 and Ser-375 by MAPK14 is required for binding to 14-3-3 proteins.

Similarity:
Belongs to the MPI phosphatase family.
Contains 1 rhodanese domain.

Database links:

Entrez Gene: 994 Human

Entrez Gene: 12531 Mouse

Entrez Gene: 171103 Rat

Omim: 116949 Human

SwissProt: P30305 Human

SwissProt: P30306 Mouse

SwissProt: P48966 Rat

Unigene: 153752 Human

Unigene: 38444 Mouse

Unigene: 11312 Rat

 



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 91久久精品国产91久久性色也 | 成网在线看 | 日韩视频一区尤物少妇偷拍 | 性生大片免费观看网站蜜芽 | 亚洲精品一区二区另类图片 | 色97色成人 | 亚洲一区二区三区色噜噜 | 漂亮人妻中文字幕丝袜 | 精品国产欧美日韩不卡在线观看 | 亚洲日韩一区精品射精 | 久久人人槡人妻人人玩夜色AV | 国产精品免费一区二区三区观看 | 97SE亚洲国产综合自在线 | 久久久精品一区二区三区 | 日日干夜夜爽 | 99久久久久免费精品国产 | 亚洲男同帅GAY片在线观看 | 午夜一级黄色大片 | 在线视频观看国产 | 丰满五十六十老熟女hd | 麻豆嫩芽忘忧草一区二区三区 | 一区二区久久久久 | 久久99热狠狠色一区二区 | 国产精品美女久久久久久 | 日韩精品美腿丝袜 | 欧美日韩视频在线播放 | 亚洲欧洲老熟女AV | 国产真实乱对白精彩久久老熟妇女 | 久久国产亚洲精品 | 九九热线视频只有这里最精品 | baoyu133.con永久免费视频 | 955cc欧美在线播放 | 加勒比HEZYO无码专区 | 歐美性受XXXX黑人XYX性爽 | 成人国产精品色哟哟 | 欧美日韩一区二区国产 | 在线观看av一区二区 | 亚洲色大网站WWW永久网站 | 成人欧美大片免费观看 | 免费91看片 | 色婷婷五月天 |