97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
baoyu116.永久免费视频,免费乱理伦片在线观看2017,日日干天天
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-VAV1/Gold Conjugated antibody (bs-4167R-Gold)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產品編號 bs-4167R-Gold
英文名稱 Rabbit Anti-VAV1/Gold Conjugated antibody
中文名稱 膠體金標記的鳥苷酸轉換因子VAV1抗體
別    名 Oncogene vav; p95Vav; Protooncogene vav; Proto-oncogene vav; VAV 1; VAV 1 oncogene; VAV; Vav proto oncogene; Vav proto-oncogene; VAV_HUMAN; VAV1.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 腫瘤  免疫學  染色質和核信號  信號轉導  轉錄調節因子  G蛋白偶聯受體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human,  (predicted: Mouse, Rat, Pig, Cow, Horse, )
產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 98kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human VAV1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產品介紹 background:
This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Apr 2012].

Function:
Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation.

Subunit:
May interact with CCPG1. Interacts with APS, DOCK2, GRB2, GRB3, DOCK2, SLA, TEC and ZNF655/VIK. Interacts with SIAH2; without leading to its degradation. Associates with BLNK, PLCG1, GRB2 and NCK1 in a B-cell antigen receptor-dependent fashion. Interacts with CBLB; which inhibits tyrosine phosphorylation and down-regulates activity. Interacts with SHB and CLNK. Interacts with THEMIS2. Interacts with HCK. Interacts with NEK3 and this interaction is prolactin-dependent. Interacts with ITK. Interacts with PTK2B/PYK2. Interacts (via SH2 domain) with SYK. Interacts with ANKRD54.

Tissue Specificity:
Widely expressed in hematopoietic cells but not in other cell types.

Post-translational modifications:
Phosphorylated on tyrosine residues by HCK in response to IFNG and bacterial lipopolysaccharide (LPS). Phosphorylated by FYN.

Similarity:
Contains 1 CH (calponin-homology) domain.
Contains 1 DH (DBL-homology) domain.
Contains 1 PH domain.
Contains 1 phorbol-ester/DAG-type zinc finger.
Contains 1 SH2 domain.
Contains 2 SH3 domains.

Database links:

Entrez Gene: 7409 Human

Entrez Gene: 22324 Mouse

Entrez Gene: 25156 Rat

Omim: 164875 Human

SwissProt: P15498 Human

SwissProt: P27870 Mouse

SwissProt: P54100 Rat

Unigene: 116237 Human

Unigene: 248172 Mouse

Unigene: 48861 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Vav1蛋白是特異于造血細胞表達的鳥苷酸轉換因子,它參與了多種免疫細胞如T細胞,B細胞,巨噬細胞,自然殺傷性細胞等的胞內信號轉導,發揮著重要作用. Vav1主要參與T細胞信號傳導途徑,傳導信號激活鈣流、細胞外信號調節激酶(ERK)以及轉錄因子NFκB。Vav1蛋白在T細胞生長發育、成熟T細胞激活、細胞因子合成及細胞骨架活動中發揮重要作用。
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 给老师下药挺进她的身体 | 操大爷影院 | 大胆av | 亚洲av网址在线观看 | 一区二区三区国产免费 | 大地资源第二页中文高清版 | 美女一区二区三区视频 | 亚洲欧洲一区二区三区 | 8x福利第一导航 | 人人爱人人做 | 国产丝袜美女一区二区三区 | 亚洲3p激情在线观看 | 成人午夜免费无码视频在线观看 | 91视频在线 | 日韩欧美精品在线视频 | 国产偷久久一级精品 | 亚洲在线免费视频 | 国产精品无码无卡在线观看久 | 亚洲无码专区三区在线观看 | 狂猛欧美激情性xxxx在线观看 | 亚洲天堂avtt| 色老板精品视频在线观看 | 欧美a级v片在线观看 | 伊人福利 | 激情三级| 久久亚洲aⅴ永久无码精品 精品久久久久久久久久ntr影视 | 欧洲国产精品无码专区影院 | 亚洲VS成人无码人在线观看堂 | 久久66热人妻偷产国产 | 一级黄色日本 | 欧美精品久久久久久久久免 | 91丨porny丨 | 国产A级毛片色咪味 | 久久av资源| anquye在线观看 | 男男GV白嫩小受GV在线播放 | 免费看一级黄色 | 亚洲另类第一页 | 亚洲精品综合精品自拍 | 国产极品99热在线播放69 | 斗破苍穹年番观看免费完整观看 |