97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
久久97精品,中文字幕国内自拍,披按摩高潮A片一区二区三区
首頁 > 產(chǎn)品中心 > 標記一抗 > 產(chǎn)品信息
Rabbit Anti-MAD2/BF488 Conjugated antibody (bs-5731R-BF488)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-5731R-BF488
英文名稱 Rabbit Anti-MAD2/BF488 Conjugated antibody
中文名稱 BF488標記的有絲分裂阻滯缺陷2樣蛋白1抗體
別    名 HSMAD2; Human mitotic feedback control protein Madp2 homolog mRNA complete cds; MAD 2; MAD2 like 1; MAD2 mitotic arrest deficient like 1; MAD2B; MAD2L1; Mitotic arrest deficient 2; Mitotic spindle assembly checkpoint protein MAD2A; REV7; MD2L1_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 腫瘤  細胞生物  免疫學(xué)  細胞周期蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 23kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Mad2L1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
MAD2L1 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. MAD2L1 is related to the MAD2L2 gene located on chromosome 1. A MAD2 pseudogene has been mapped to chromosome 14. [provided by RefSeq, Jul 2008]

Function:
Component of the spindle-assembly checkpoint thatprevents the onset of anaphase until all chromosomes are properlyaligned at the metaphase plate. Required for the execution of themitotic checkpoint which monitors the process ofkinetochore-spindle attachment and inhibits the activity of theanaphase promoting complex by sequestering CDC20 until allchromosomes are aligned at the metaphase plate.

Subunit:
Monomer and homodimer. Heterotetramer with MAD1L1. Formation of a heterotetrameric core complex containing two molecules each of MAD1L1 and of MAD2L1 promotes binding of another molecule of MAD2L1 to each MAD2L1, resulting in a heterohexamer. Interacts with CDC20, MAD2L1BP and with ADAM17/TACE. Dimeric MAD2L1 in the closed conformation interacts with CDC20. Monomeric MAD2L1 in the open conformation does not interact with CDC20. CDC20 competes with MAD1L1 for MAD2L1 binding. Interacts with TPR. Binds to UBD during mitosis. Interacts with isoform 1 and isoform 2 of NEK2.

Subcellular Location:
Nucleus. Chromosome, centromere, kinetochore. Cytoplasm. Cytoplasm, cytoskeleton, spindle pole.

Post-translational modifications:
Phosphorylated on multiple serine residues. The level ofphosphorylation varies during the cell cycle and is highest duringmitosis. Phosphorylation abolishes interaction with MAD1L1 andreduces interaction with CDC20. Phosphorylated by NEK2.

Similarity:
Belongs to the MAD2 family. Contains 1 HORMA domain.

Database links:

Entrez Gene: 4085 Human

Omim: 601467 Human

SwissProt: Q13257 Human

Unigene: 591697 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.kastlife.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
主站蜘蛛池模板: 中文字幕在线中文 | 久久免费观看少妇a级毛片 正能量免费网站WWW正能量免费 | 欧美视频www | 特黄大片AAAAA毛片 | 成人国产精品一区在线观看播放 | 亚欧日韩在线 | 色视频一区 | 一级做性色a爱片久久毛片欧 | 深夜视频在线免费 | 国产欧美久久一区二区三区 | 中文字幕日韩精品视频一区视频二区 | 草久久久久 | www.国产网站| 亚洲欧美日韩在线观看一区二区三区 | 欧美日韩亚洲中文 | 国产精品色区 | 天天玩天天操天天干 | 久久99亚洲精品久久99果 | 孕妇奶水仑乱A级毛片免费看 | 伦理片一级片 | 日韩欧美成人一区二区三区 | 99视频在线无码 | 久久99久久精品国产 | 15p亚洲 | 乱人伦人妻中文字幕 | 无码少妇高潮喷水A片免费 欧美性xxxx视频 | 精品国产麻豆一区二区三区 | 人av在线| 4438五月综合 | 内射白浆一区二区在线观看 | 国产亚洲精品久久久999密壂 | 91超碰caoporm国产香蕉 | 狠狠躁狠狠爱免费视频欧美 | 67PAO国产成视频永久免费 | 久久精品水蜜桃AV综合天堂 | 在线观看欧美日韩国产 | 免费看淫片 | 国产成人精品福利 | 日韩av一区二区三区四区 | 99国产精品国产免费观看 | 一本久道久久综合狠狠爱 |