97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
免费看片AV免费大片,天天看片天天操,日韩欧美的一区二区
Rabbit Anti-ENSA/Biotin Conjugated antibody (bs-11793R-Bio)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-11793R-Bio
英文名稱 Rabbit Anti-ENSA/Biotin Conjugated antibody
中文名稱 生物素標(biāo)記的α內(nèi)磺肽抗體
別    名 Alpha endosulfine; ARPP 19e; Endosulfine alpha; ENSA_HUMAN; Alpha-endosulfine; ARPP-19e.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 神經(jīng)生物學(xué)  生長因子和激素  通道蛋白  細(xì)胞膜受體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, )
產(chǎn)品應(yīng)用 WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 13kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ENSA/ARPP-19
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The protein encoded by this gene belongs to a highly conserved cAMP-regulated phosphoprotein (ARPP) family. This protein was identified as an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. ABCC8 is the regulatory subunit of the ATP-sensitive potassium (KATP) channel, which is located on the plasma membrane of pancreatic beta cells and plays a key role in the control of insulin release from pancreatic beta cells. This protein is thought to be an endogenous regulator of KATP channels. In vitro studies have demonstrated that this protein modulates insulin secretion through the interaction with KATP channel, and this gene has been proposed as a candidate gene for type 2 diabetes. At least eight alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]

Function:
ENSA (Alpha endosulfine) is expressed in a wide range of tissues including muscle, brain, and endocrine tissues. The recombinant protein inhibits binding of labeled glibenclamide to beta cell membranes. It also inhibits cloned K(ATP) channel currents and thereby stimulates insulin secretion. It was proposed that endosulfine is an endogenous regulator of the K(ATP) channel, which has a key role in the control of insulin release and, more generally, couples cell metabolism to electrical activity.

Subunit:
Interacts (when phosphorylated at Ser-67) with PPP2R2D. Interacts with ABCC8. Interacts with SNCA; interaction is disrupted when phosphorylated at Ser-109.

Subcellular Location:
Cytoplasmic

Tissue Specificity:
Widely expressed with high levels in skeletal muscle and brain and lower levels in the pancreas.

Post-translational modifications:
Phosphorylation at Ser-67 by GWL during mitosis is essential for interaction with PPP2R2D (PR55-delta) and subsequent inactivation of PP2A (By similarity). Phosphorylated by PKA.

Similarity:
Belongs to the endosulfine family.

Database links:

Entrez Gene: 281142 Cow

Entrez Gene: 2029 Human

Entrez Gene: 56205 Mouse

Entrez Gene: 60334 Rat

Omim: 603061 Human

SwissProt: O43768 Human

SwissProt: P60840 Mouse

SwissProt: P60841 Rat

Unigene: 632456 Human

Unigene: 27154 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.kastlife.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
主站蜘蛛池模板: 精品无码人妻夜人多侵犯18 | 国产欧美一区二区精品仙草咪 | 亚洲自拍偷拍综合网 | a黄在线观看 | 久热综合网 | 亚洲夜幕久久日韩精品一区 | 久久免费在线观看视频 | 黄色大片视频 | 日韩久久无码免费看A | 小小拗女一区二区三区 | 爱情岛论坛自拍亚洲品质极速福利 | 精品综合久久久久久888蜜芽 | 国产AV永久无码精品网站 | 99在线在线视频免费视频观看 | 国产精品人人妻人人爽人人牛 | 美女一区二区三区视频 | 亚洲调教色xxxxx亚洲 | 国产亚洲精品资源在线26u91 | 精品卡一卡二卡3卡高清乱码 | 国产激情无码视频在线播放性色 | 精品国产AⅤ一区二区三区V免费 | 中日黄色一级片 | 日韩人妻精品一区二区三区视频 | 狠狠色成人综合网 | 欧美成人影片 | 国产女教师一爽a片 | 欧美综合一区二区 | 色啪视频 | 斗罗大陆4终极斗罗免费观看 | 91精品国产综合久久久久久蜜月 | 国产精品三级在线观看无码 | 一区二区三区四区五区中文字幕 | 91亚洲一区二区 | 91蜜臀精品国产自偷在线 | 久久99精品久久久久久久久久 | 无码AV波多野结衣久久 | 欧美日韩国产高清 | 久久久精品国产免费观看一区二区 | 久久久久久免费免费 | 视频亚洲区 | 肉岳疯狂69式激情的高潮 |