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Rabbit Anti-IQGAP3/Gold Conjugated antibody (bs-11856R-Gold)
訂購熱線:400-901-9800
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訂購QQ:  400-901-9800
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產品編號 bs-11856R-Gold
英文名稱 Rabbit Anti-IQGAP3/Gold Conjugated antibody
中文名稱 膠體金標記的RasGTP酶激活蛋白IQGAP3抗體
別    名 IQ motif containing GTPase activating protein 3; IQGA3_HUMAN; IQGAP 3 ; IQGAP3; MGC10170; MGC10831; MGC1947 antibodyOTTHUMP00000031854 ; OTTHUMP00000031855; Ras GTPase activating like protein IQGAP3; Ras GTPase-activating-like protein IQGAP3.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 腫瘤  神經生物學  信號轉導  細胞膜受體  G蛋白偶聯受體  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, )
產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 185kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human IQGAP3
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產品介紹 background:
IQGAP3 is a 1,631 amino acid protein that acts as an effector of Cdc42 and Rac 1, linking their activation to the cytoskeleton during neuronal morphogenesis. A novel member of the IQGAP family, IQGAP3 is highly expressed in brain where it localizes to axons of hippocampal neurons. IQGAP3 contains one Ras-GAP domain, a CH (calponin-homology) domain, four IQ domains and is encoded by a gene located on human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.

Similarity:
Contains 1 CH (calponin-homology) domain.
Contains 4 IQ domains.
Contains 1 Ras-GAP domain.

Database links:

Entrez Gene: 128239 Human

Entrez Gene: 404710 Mouse

Entrez Gene: 310621 Rat

SwissProt: Q86VI3 Human

Unigene: 591495 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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