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Rabbit Anti-LR8/Gold Conjugated antibody (bs-11876R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-11876R-Gold
英文名稱 Rabbit Anti-LR8/Gold Conjugated antibody
中文名稱 膠體金標(biāo)記的跨膜蛋白TMEM176B抗體
別    名 LR 8; TMEM176B; Transmembrane protein 176B; T176B_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  細(xì)胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 29kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human LR8/TMEM176B
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
Chromosome 7 is about 158 milllion bases long, encodes over 1000 genes and makes up about 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders including cases of acute myelogenous leukemia and myelodysplasia. The LR8 gene product has been provisionally designated LR8 pending further characterization.

Function:
LR8 may be involved in the control of dendritic cell maturation and thus may play a role in the induction or maintenance of allograft tolerance. It's function is unknown.

Subcellular Location:
Nuclear membrane; Multi pass membrane protein.

Tissue Specificity:
Expressed in lung and dermal fibroblasts.

Similarity:
Belongs to the TMEM176 family.

Database links:

Entrez Gene: 28959 Human

Omim: 610385 Human

SwissProt: Q3YBM2 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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