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Rabbit Anti-LR8/RBITC Conjugated antibody (bs-11876R-RBITC)
訂購熱線:400-901-9800
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-11876R-RBITC
英文名稱 Rabbit Anti-LR8/RBITC Conjugated antibody
中文名稱 羅丹明(RBITC)標記的跨膜蛋白TMEM176B抗體
別    名 LR 8; TMEM176B; Transmembrane protein 176B; T176B_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  神經生物學  細胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 29kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human LR8/TMEM176B
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Chromosome 7 is about 158 milllion bases long, encodes over 1000 genes and makes up about 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders including cases of acute myelogenous leukemia and myelodysplasia. The LR8 gene product has been provisionally designated LR8 pending further characterization.

Function:
LR8 may be involved in the control of dendritic cell maturation and thus may play a role in the induction or maintenance of allograft tolerance. It's function is unknown.

Subcellular Location:
Nuclear membrane; Multi pass membrane protein.

Tissue Specificity:
Expressed in lung and dermal fibroblasts.

Similarity:
Belongs to the TMEM176 family.

Database links:

Entrez Gene: 28959 Human

Omim: 610385 Human

SwissProt: Q3YBM2 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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