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Rabbit Anti-NAV2/Gold Conjugated antibody (bs-11892R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產品編號 bs-11892R-Gold
英文名稱 Rabbit Anti-NAV2/Gold Conjugated antibody
中文名稱 膠體金標記的維甲酸誘導神經母細胞瘤蛋白1抗體
別    名 HELAD1; Helicase, APC down regulated 1; KIAA1419; mCG 145366; mKIAA3015; NAV 2; Neuron navigator 2; POMFIL2; Pore membrane and/or filament interacting like protein 2; RAINB1; RAINB2; Retinoic acid inducible in neuroblastoma 1; Steerin 2; STEERIN2; Unc 53 homolog 2; Unc53H2; NAV2_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 腫瘤  細胞生物  神經生物學  腫瘤細胞生物標志物  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human,  (predicted: Mouse, Dog, Cow, Horse, Rabbit, )
產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 268kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NAV2/RAINB1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產品介紹 background:
This gene encodes a member of the neuron navigator gene family, which may play a role in cellular growth and migration. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

Function:
NAV2 protein shows high similarity to Caenorhabditis elegans, unc-53, that is required for axonal elongation of mechanosensory neurons, suggesting that these proteins are orthologs. Thus, NAV2 may be involved in the vitamin A metabolite, atRA (all-trans retinoic acid)-mediated neurite outgrowth. NAV2 possesses 3' to 5' helicase activity and exonuclease activity and is involved in the development of different sensory organs.

Subcellular Location:
Nuclear.

Tissue Specificity:
Highly expressed in the brain, kidney and liver. Also expressed in the thyroid, mammary gland, spinal cord, heart, placenta and lung. Abundantly expressed in colon cancers.

Similarity:
Belongs to the Nav/unc-53 family.
Contains 1 CH (calponin-homology) domain.

Database links:

Entrez Gene: 89797 Human

Omim: 607026 Human

SwissProt: Q8IVL1 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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