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Rabbit Anti-NRSN1/Gold Conjugated antibody (bs-11915R-Gold)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產品編號 bs-11915R-Gold
英文名稱 Rabbit Anti-NRSN1/Gold Conjugated antibody
中文名稱 膠體金標記的神經囊泡膜蛋白1抗體
別    名 Neurensin-1; Neuro-p24; NRSN1; NRSN1_HUMAN; p24; Vesicular membrane protein of 24 kDa; Vesicular membrane protein p24; VMP.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 細胞生物  發育生物學  神經生物學  信號轉導  細胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Horse, Rabbit, )
產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 21kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NRSN1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產品介紹 background:
Neurensin-1 (NRSN1), also designated Vesicular membrane protein of 24 kDa (VMP) or Neuro-p24, is a 195 amino acid multi-pass membrane protein belonging to the VMP family that is involved in the transport of neural organelle transport and in the transduction of nerve signals or in nerve growth. Expressed solely in brain, Neurensin-1 is also thought to play a role in neurite extension. The gene encoding Neurensin-2 maps to human chromosome 6, which contains around 1,200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6.

Function:
May play an important role in neural organelle transport, and in transduction of nerve signals or in nerve growth. May play a role in neurite extension.

Subcellular Location:
Membrane. Localizes mainly to neurites.

Tissue Specificity:
Expressed in brain. Not detectable in other tissues tested.

Similarity:
Belongs to the VMP family.

Database links:

Entrez Gene: 140767 Human

Entrez Gene: 22360 Mouse

Entrez Gene: 291129 Rat

SwissProt: Q8IZ57 Human

SwissProt: P97799 Mouse

Unigene: 726270 Human

Unigene: 4766 Mouse

Unigene: 225156 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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