97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
成人三级在线,免费日韩av在线播放,精品国产性色无码av网站
Rabbit Anti-LC3B/BF350 Conjugated antibody (bs-4843R-BF350)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號 bs-4843R-BF350
英文名稱 Rabbit Anti-LC3B/BF350 Conjugated antibody
中文名稱 BF350標(biāo)記的自噬微管相關(guān)蛋白輕鏈β3抗體
別    名 Microtubule-associated protein 1 light chain 3 beta; ATG8F; Autophagy related protein LC3 B; Autophagy related ubiquitin like modifier LC3 B; Autophagy-related protein LC3 B; Autophagy-related ubiquitin-like modifier LC3 B; MAP1 light chain 3 like protein 2; MAP1 light chain 3-like protein 2; MAP1A/1B light chain 3 B; MAP1A/1BLC3; MAP1A/MAP1B LC3 B; MAP1A/MAP1B light chain 3 B; MAP1ALC3; MAP1LC3B; Microtubule associated protein 1 light chain 3 beta; Microtubule associated proteins 1A/1B light chain 3B; Microtubule-associated protein 1 light chain 3 beta; Microtubule-associated proteins 1A/1B light chain 3B; MLP3B_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 腫瘤  細(xì)胞生物  神經(jīng)生物學(xué)  信號轉(zhuǎn)導(dǎo)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse, Rat,  (predicted: Human, Chicken, Cow, Danio rerio)
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 14kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse Microtubule-associated proteins 1A/1B light chain 3B
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Microtubule-associated proteins (MAPs) regulate microtubule stability and play critical roles in neuronal development and in maintaining the balance between neuronal plasticity and rigidity. MAP-light chain 3 beta (MAP-LC3 Beta) and MAP-light chain 3 alpha (MAP-LC3 Alpha) are subunits of both MAP1A and MAP1B. MAP-LC3 Beta, a homolog of Apg8p, is essential for autophagy and associated to the autophagosome membranes after processing. Two forms of LC3 Beta, the cytosolic LC3-I and the membrane-bound LC3-II, are produced post-translationally. LC3-I is formed by the removal of the C-terminal 22 amino acids from newly synthesized LC3 Beta, followed by the conversion of a fraction of LC3-I into LC3-II. LC3 enhances fibronectin mRNA translation in ductus arteriosus cells through association with 60S ribosomes and binding to an AU-rich element in the 3’ untranslated region of fibronectin mRNA. This facilitates sorting of fibronectin mRNA onto rough endoplasmic reticulum and translation. MAP LC3 Beta may also be involved in formation of autophagosomal vacuoles. It is expressed primarily in heart, testis, brain and skeletal muscle.

Function:
Probably involved in formation of autophagosomal vacuoles

Subunit:
3 different light chains, LC1, LC2 and LC3, can associate with MAP1A and MAP1B proteins. Interacts at microtubules with CABP1 (via EF-hands 1 and 2) but not with calmodulin. Interacts with FYCO1 (via C-terminus). Interacts with TP53INP1 and TP53INP2. Interacts with TBC1D25. Directly interacts with SQSTM1; this interaction leads to MAP1LC3B recruitment to inclusion bodies containing polyubiquitinated protein aggregates and to inclusion body degradation by autophagy.

Subcellular Location:
Cytoplasm, cytoskeleton. Endomembrane system; Lipid-anchor. Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Note=LC3-II binds to the autophagic membranes.

Tissue Specificity:
Most abundant in heart, brain, skeletal muscle and testis. Little expression observed in liver.

Post-translational modifications:
The precursor molecule is cleaved by APG4B/ATG4B to form LC3-I. This is activated by APG7L/ATG7, transferred to ATG3 and conjugated to phospholipid to form LC3-II.

Similarity:
Belongs to the MAP1 LC3 family.

Database links:

Entrez Gene: 81631 Human

Entrez Gene: 427559 Chicken

Entrez Gene: 408001 Cow

Entrez Gene: 67443 Mouse

Entrez Gene: 64862 Rat

Omim: 609604 Human

SwissProt: O41515 Cow

SwissProt: Q9GZQ8 Human

SwissProt: Q9CQV6 Mouse

SwissProt: Q62625 Rat

Unigene: 356061 Human

Unigene: 28357 Mouse

Unigene: 41412 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.kastlife.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
主站蜘蛛池模板: 伊人狠狠干 | 国产精品久久久久婷婷五月 | 久久精品在线 | 夜夜爽WWW | 手机在线一区 | 欧洲国产精品无码专区影院 | 久久韩日| 孩交精品XXXX视频视频 | 欧美性猛交久久久乱大交小说 | 超碰97精品| a级国产乱理伦片在线观看 www在线免费 | 国产麻豆| 精品91在线视频 | 一本之道高清无码视频 | 国产无套激情在线视频 | 国产精品无码无卡无需播放器 | 另类色综合| 在线观看av网 | 国产娱乐凹凸视觉盛宴在线视频 | 日本黄色免费视频 | 日韩一区二区三区四区区区 | 亚洲人成精品久久久久 | 日韩精品一区二区三区中文无码 | 少妇又色又爽又高潮 | 久久99精品久久久噜噜最新章节 | 一区二区三区高清在线视频 | 最近日本MV字幕免费观看 | 四虎影视永久免费在线观看 | 蜜臀亚洲AV无码精品国产午夜. | 亚洲V国产V天堂A无码二区 | 爆乳情帝国网综合社区 | 小嫩嫩12欧美 | 国产欧美一区二区三区视频 | 亚洲精品456在线播放第一页 | 久久精品一区中文字幕 | 国产V亚洲V天堂A无码 | 亚洲在线免费观看视频 | 欧美成人伊人久久综合网 | 亚洲AV综合一区二区在线观看 | 国产欧美视频一区二区三区 | 久久频这里精品99香蕉 |