97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
国产女同疯狂作爱系列2,久久久成人免费一区二区,久久久久国
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-LC3B/PE-Cy5.5 Conjugated antibody (bs-4843R-PE-Cy5.5)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-4843R-PE-Cy5.5
英文名稱 Rabbit Anti-LC3B/PE-Cy5.5 Conjugated antibody
中文名稱 PE-Cy5.5標記的自噬微管相關蛋白輕鏈β3抗體
別    名 Microtubule-associated protein 1 light chain 3 beta; ATG8F; Autophagy related protein LC3 B; Autophagy related ubiquitin like modifier LC3 B; Autophagy-related protein LC3 B; Autophagy-related ubiquitin-like modifier LC3 B; MAP1 light chain 3 like protein 2; MAP1 light chain 3-like protein 2; MAP1A/1B light chain 3 B; MAP1A/1BLC3; MAP1A/MAP1B LC3 B; MAP1A/MAP1B light chain 3 B; MAP1ALC3; MAP1LC3B; Microtubule associated protein 1 light chain 3 beta; Microtubule associated proteins 1A/1B light chain 3B; Microtubule-associated protein 1 light chain 3 beta; Microtubule-associated proteins 1A/1B light chain 3B; MLP3B_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  神經生物學  信號轉導  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse, Rat,  (predicted: Human, Chicken, Cow, Danio rerio)
產品應用 Flow-Cyt=1:50-200 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 14kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse Microtubule-associated proteins 1A/1B light chain 3B
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Microtubule-associated proteins (MAPs) regulate microtubule stability and play critical roles in neuronal development and in maintaining the balance between neuronal plasticity and rigidity. MAP-light chain 3 beta (MAP-LC3 Beta) and MAP-light chain 3 alpha (MAP-LC3 Alpha) are subunits of both MAP1A and MAP1B. MAP-LC3 Beta, a homolog of Apg8p, is essential for autophagy and associated to the autophagosome membranes after processing. Two forms of LC3 Beta, the cytosolic LC3-I and the membrane-bound LC3-II, are produced post-translationally. LC3-I is formed by the removal of the C-terminal 22 amino acids from newly synthesized LC3 Beta, followed by the conversion of a fraction of LC3-I into LC3-II. LC3 enhances fibronectin mRNA translation in ductus arteriosus cells through association with 60S ribosomes and binding to an AU-rich element in the 3’ untranslated region of fibronectin mRNA. This facilitates sorting of fibronectin mRNA onto rough endoplasmic reticulum and translation. MAP LC3 Beta may also be involved in formation of autophagosomal vacuoles. It is expressed primarily in heart, testis, brain and skeletal muscle.

Function:
Probably involved in formation of autophagosomal vacuoles

Subunit:
3 different light chains, LC1, LC2 and LC3, can associate with MAP1A and MAP1B proteins. Interacts at microtubules with CABP1 (via EF-hands 1 and 2) but not with calmodulin. Interacts with FYCO1 (via C-terminus). Interacts with TP53INP1 and TP53INP2. Interacts with TBC1D25. Directly interacts with SQSTM1; this interaction leads to MAP1LC3B recruitment to inclusion bodies containing polyubiquitinated protein aggregates and to inclusion body degradation by autophagy.

Subcellular Location:
Cytoplasm, cytoskeleton. Endomembrane system; Lipid-anchor. Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Note=LC3-II binds to the autophagic membranes.

Tissue Specificity:
Most abundant in heart, brain, skeletal muscle and testis. Little expression observed in liver.

Post-translational modifications:
The precursor molecule is cleaved by APG4B/ATG4B to form LC3-I. This is activated by APG7L/ATG7, transferred to ATG3 and conjugated to phospholipid to form LC3-II.

Similarity:
Belongs to the MAP1 LC3 family.

Database links:

Entrez Gene: 81631 Human

Entrez Gene: 427559 Chicken

Entrez Gene: 408001 Cow

Entrez Gene: 67443 Mouse

Entrez Gene: 64862 Rat

Omim: 609604 Human

SwissProt: O41515 Cow

SwissProt: Q9GZQ8 Human

SwissProt: Q9CQV6 Mouse

SwissProt: Q62625 Rat

Unigene: 356061 Human

Unigene: 28357 Mouse

Unigene: 41412 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 97亚洲色欲色欲综合网 | 亚洲成人生活片 | 国产精品久久久久久久久久新婚 | 中文字幕亚洲一区一区 | 日韩黄色在线播放 | 特级全黄男女交高清视频在线观看 | 国产被窝福利一区二区 | 国产理论一区二区三区 | 欧美福利片在线观看 | 久久不见久久见www免费视频 | 成人av视频在线观看 | 欧美一二三| 黄色a级片网站 | 精品一二三区久久aaa片 | 免费观看作爱视频网站 | 国产精品91xxx | 日日碰狠狠添天天爽超碰97久久 | 又黄又爽又刺激的视频 | 青草福利 | 日本国产黄色 | 偷窥国产亚洲免费视频 | 国产极品99热在线播放69 | 亚洲综合站| 无套内射chinesehd熟女 | 一区二区三区日本 | 我要看免费毛片 | 日韩视频中文字幕视频一区 | 麻豆传媒视频在线播放 | 免费又黄又爽又猛大片午夜 | 真人一级毛片视频 | av免费在线播放网址 | xvideos中文版网站入口 | 又黄又粗又爽免费观看 | 99久久久国产精品免费蜜臀 | 国内外精品激情刺激在线 | 中国一级毛片免费看 | 国产精品日韩专区 | 最新国产福利 | 激情国产AV做激情国产爱 | 996热re视频精品视频这里 | eeuss影院www免费播放 |