97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
日韩欧美中文免费,国产精品嫩草影院在线看,婷婷一二区
Rabbit Anti-CACNB4/Cy5.5 Conjugated antibody (bs-11983R-Cy5.5)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-11983R-Cy5.5
英文名稱 Rabbit Anti-CACNB4/Cy5.5 Conjugated antibody
中文名稱 Cy5.5標(biāo)記的L型電壓依賴型鈣通道β4抗體
別    名 CAB4; L-type Ca++ CPβ4; CACB4_HUMAN; Cacnb4; CACNLB4; Calcium channel voltage dependent beta 4 subunit; Calcium channel voltage dependent subunit beta 4; Calcium channel voltage-dependent subunit beta 4; Dihydropyridine sensitive L type calcium channel beta 4 subunit; EA5; EIG9; EJM; EJM4; Voltage-dependent L-type calcium channel subunit beta-4.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  信號轉(zhuǎn)導(dǎo)  通道蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Sheep, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 58kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CACNB4/L-type Ca++ CPβ4
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Voltage-dependent calcium channels are essential for the release of neurotransmitters. L-type (long lasting current) voltage-dependent calcium channels are composed of four subunits: an Alpha1 subunit, a Beta subunit, a Beta subunit and an Alpha2 Gamma subunit. The Beta subunit is encoded by four genes, designated Beta1-Beta 4, all of which contribute to the diversity of calcium currents and are involved in membrane trafficking of the Beta subunit. L-type Ca++ CP Beta 4, also known as CACNB4 (Calcium channel voltage-dependent subunit beta 4), CACNLB4 or CAB4, is a 484 amino acid protein that contains one SH3 domain and is expressed in ovary, brain and smooth muscle. Functioning as one of the four components of the Beta subunit, L-type Ca++ CP Beta 4 increases the peak calcium current in voltage-dependent calcium channels, thereby shifting the voltage dependencies of activation and inactivation and controlling G protein inhibition and Beta membrane targeting. Two isoforms of L-type Ca++ CP Beta4 exist due to alternative splicing events.

Function:
The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.

Subunit:
The L-type calcium channel is composed of four subunits: alpha-1, alpha-2, beta and gamma. Interacts with FASLG.

Tissue Specificity:
Expressed predominantly in the cerebellum and kidney.

DISEASE:
Genetic variations in CACNB4 are the cause of susceptibility to idiopathic generalized epilepsy type 9 (IGE9) [MIM:607682]. IGE9 is characterized by recurring generalized seizures in the absence of detectable brain lesions and/or metabolic abnormalities. Generalized seizures arise diffusely and simultaneously from both hemispheres of the brain.
Genetic variations in CACNB4 are the cause of susceptibility to juvenile myoclonic epilepsy type 6 (EJM6) [MIM:607682]. EJM6 is a subtype of idiopathic generalized epilepsy. Patients have afebrile seizures only, with onset in adolescence (rather than in childhood) and myoclonic jerks which usually occur after awakening and are triggered by sleep deprivation and fatigue.

Similarity:
Belongs to the calcium channel beta subunit family.
Contains 1 SH3 domain.

Database links:

Entrez Gene: 785 Human

Entrez Gene: 12298 Mouse

Entrez Gene: 58942 Rat

Omim: 601949 Human

SwissProt: O00305 Human

SwissProt: Q8R0S4 Mouse

Unigene: 120725 Human

Unigene: 330223 Mouse

Unigene: 472778 Mouse

Unigene: 9863 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.kastlife.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
主站蜘蛛池模板: 日韩中文字幕免费观看 | 国产精品极品美女自在线观看免费 | 国产在线啪 | 91久久人澡人人添人人爽欧美 | 欧美精品福利视频 | 成人av专区 | 视频免费一区 | 99久久免费只有精品国产高潮 | 最新av免费在线 | 人人妻人人妻人人片av | 国模av在线 | 久久国产欧美一区二区三区免费 | 精品久久久一区 | 国产日韩在线观看视频 | 日韩视频在线观看不卡 | 日日躁夜夜躁aaaaxxxx | 美丽姑娘免费高清观看 | 91动漫网站 | 国产欧美日韩在线观看一区二区 | 国产国拍亚洲精品在线 | 国产视频不卡一区 | 人av在线| 欧美性猛交xxxx乱大交免费看 | 精品丝袜国产自在线拍高清 | 成人片段大有上在线观看 | 男人操女人视频免费 | 亚洲中文久久精品81 | 青青视频免费观看 | 成人黄网视频在线观看 | 好久不见在线观看免费高清 | 久热这里只有精品6 | 国产精品久久久久久久久免费蜜臀 | 美国精品一区二区 | 日本久久99| 免费亚洲视频在线观看 | 日本十八禁视频无遮挡 | 人妻系列无码专区无码专区 | 狠狠色丁香婷婷综合久久来来去 | 4438成人网 | 精品亚洲国产成人A片在线鸭王 | 91久久一区二区 |