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Rabbit Anti-P2RX6/BF488 Conjugated antibody (bs-12110R-BF488)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-12110R-BF488
英文名稱 Rabbit Anti-P2RX6/BF488 Conjugated antibody
中文名稱 BF488標(biāo)記的三磷酸腺苷受體P2X6抗體
別    名 ATP receptor; P2RX6; P2RX6_HUMAN; P2RXL1; P2X purinoceptor 6; P2X6; P2XM; Purinergic receptor; Purinergic receptor P2X like 1; Purinergic receptor P2X-like 1; Skeletal muscle expressed P2X.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 腫瘤  神經(jīng)生物學(xué)  信號轉(zhuǎn)導(dǎo)  細(xì)胞凋亡  通道蛋白  細(xì)胞膜受體  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Pig, Horse, Rabbit, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 49kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human P2RX6
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The P2X receptor family is comprised of ligand-gated ion channels that allow for the increased permeability of calcium into the cell in response to extracellular ATP. The seven P2X receptors, P2X1-P2X7, form either homomeric or heteromeric channels or both. They are characterized by intracellular amino- and carboxy-termini. P2X receptors are expressed in a wide variety of tissues, including neurons, prostate, bladder, pancreas, colon, testis and ovary. The major function of the P2X receptors is to mediate synaptic transmissions between neurons and to other tissues via the binding of extracellular ATP, which acts as a neurotransmitter. The P2X receptors may be involved in the onset of necrosis or apoptosis after prolonged exposure to high concentrations of extracellular ATP.

Function:
Receptor for ATP that acts as a ligand-gated ion channel.

Subunit:
Functional P2XRs are organized as homomeric and heteromeric trimers

Subcellular Location:
Membrane; Multi-pass membrane protein.

Tissue Specificity:
Expressed predominantly in skeletal muscle.

Similarity:
Belongs to the P2X receptor family.

Database links:

Entrez Gene: 9127 Human

Entrez Gene: 18440 Mouse

Entrez Gene: 25041 Rat

Omim: 608077 Human

SwissProt: O15547 Human

SwissProt: O54803 Mouse

SwissProt: P51579 Rat

Unigene: 113275 Human

Unigene: 8032 Mouse

Unigene: 10258 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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