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Rabbit Anti-CPNE3/Gold Conjugated antibody (bs-14027R-Gold)
訂購熱線:400-901-9800
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產品編號 bs-14027R-Gold
英文名稱 Rabbit Anti-CPNE3/Gold Conjugated antibody
中文名稱 膠體金標記的鈣依賴膜結合蛋白Copine蛋白3抗體
別    名 Copine 3; Copine III; Copine-3; Copine3; CopineIII; CPN3; CPNE 3; CPNE3; CPNE3_HUMAN; KIAA0636; PRO1071.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 細胞生物  信號轉導  結合蛋白  細胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, )
產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 60kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CPNE3
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產品介紹 background:
Copine 3 is a member of the copine family of evolutionarily conserved, soluble, calcium-dependent, membrane-binding proteins. Members of the copine family are involved in signal transduction and membrane trafficking. Copine 3 is ubiquitously expressed and contains two N-terminal C2 domains and one C-terminal VWFA (von Willebrand factor A) domain, which is also referred to as the A domain or the core domain. As is characteristic of the copine family, copine 3 functions in membrane trafficking and is capable of binding phospholipids in a calcium-dependent manner. Differing from other members of the copine family, copine 3 may possess some intrinsic kinase activity. Copine 3 exists as a monomer in the cytosol and undergoes a conformational change upon binding to calcium.

Function:
May function in membrane trafficking. Exhibits calcium-dependent phospholipid binding properties.

Tissue Specificity:
Ubiquitous.

Post-translational modifications:
Phosphorylated on serine and threonine residues.

Similarity:
Belongs to the copine family.
Contains 2 C2 domains.
Contains 1 VWFA domain.

Database links:

Entrez Gene: 8895 Human

Entrez Gene: 615304 Cow

Entrez Gene: 70568 Mouse

Omim: 604207 Human

SwissProt: O75131 Human

SwissProt: Q8BT60 Mouse

Unigene: 191219 Human

Unigene: 38390 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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