97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
视频福利一区,亚洲欧洲在线观看视频,黄色调教视频
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-Activin Receptor Type IIB/Cy3 Conjugated antibody (bs-12417R-Cy3)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-12417R-Cy3
英文名稱 Rabbit Anti-Activin Receptor Type IIB/Cy3 Conjugated antibody
中文名稱 Cy3標記的激活素受體2B抗體
別    名 Activin Receptor Type IIB; ACTR-IIB; Activin A receptor type IIB; Activin receptor type 2B; Activin receptor type IIB; Activin receptor type-2B; ActR IIB; ACTR-IIB; ActRIIB; ACVR 2B; ACVR2B; AVR2B_HUMAN; HTX4; MGC116908.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  信號轉導  干細胞  生長因子和激素  激酶和磷酸酶  細胞表面分子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Sheep, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 56kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ACVR2B/ACTR-IIB
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Members of the transforming growth factor b superfamily bind to a pair of transmembrane proteins, known as receptor types I and II, which contain serine/threonine kinases and associate to form a signaling complex (1). Activin has been shown to bind a heteromeric noncovalent complex, which consists of a type I receptor, ACTR-IA (also designated ACVRI and ALK-2) or ACTR-IB (also designated ALK-4 and SKR2), and a type II receptor, ACTR-IIA (also designated ACVR2A) or ACTR-IIB (also designated ACVR2B) (1-6). Both receptor types are highly expressed in brain (5). The activin receptor family members are thought to mediate distinct effects on gene expression, cell differentiation, and morpho- genesis in a dose dependent fashion (5,6).

Function:
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A.

Subunit:
Forms an activin receptor complex with activin type II receptors such as ACVR1B. Interacts with VPS39.

Subcellular Location:
Cell membrane; Single-pass type I membrane protein.

Post-translational modifications:
Phosphorylated. Constitutive phosphorylation is in part catalyzed by its own kinase activity.

DISEASE:
Defects in ACVR2B are the cause of visceral heterotaxy autosomal type 4 (HTX4) [MIM:613751]. A form of visceral heterotaxy, a complex disorder due to disruption of the normal left-right asymmetry of the thoracoabdominal organs. It results in an abnormal arrangement of visceral organs, and a wide variety of congenital defects. Clinical features of visceral heterotaxy type 4 include dextrocardia, right aortic arch and a right-sided spleen, anomalies of the inferior and the superior vena cava, atrial ventricular canal defect with dextro-transposed great arteries, pulmonary stenosis, polysplenia and midline liver.

Similarity:
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.
TGFB receptor subfamily.
Contains 1 protein kinase domain.

Database links:

Entrez Gene: 93 Human

Entrez Gene: 11481 Mouse

Entrez Gene: 25366 Rat

Omim: 602730 Human

SwissProt: Q13705 Human

SwissProt: P27040 Mouse

SwissProt: P38445 Rat

Unigene: 174273 Human

Unigene: 390239 Mouse

Unigene: 24240 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 国产一区二区三区高清在线观看 | 日本在线免费 | 国产精品高清在线 | 精品久久久久久 | 久久久www免费人成精品 | 97久久夜色精品国产九色 | 国产不卡片 | 亚洲小视频网站 | 国产吹潮视频在线观看 | 人妻三级日本三级日本三级极 | 亚洲成AV人片一区二区密柚 | 在线观看av黄色 | 她似遥上月短剧免费观看 | 中文字幕日韩精品视频一区视频二区 | 亚洲国产精品久久久久 | 中国丰满熟妇xxxx性 | 蜜臀久久精品久久久久久酒店? | 老鸭窝一区 | gogogo高清在线观看中文 | 欧美乱强伦XXXX孕妇 | 欧美性free玩弄少妇 | 欧美视频在线观看 | 97色成人网 | 视频精品中文字幕一区二区 | 丝袜无码一区二区三区 | 国产AV无码专区亚洲精品 | 午夜网站在线观看 | 欧美ⅴa | 精品国产乱码久久久久久密桃99 | 国产成人午夜福利在线观看者 | 福利丝袜美腿视频网站 | 国产一区二区丁香婷婷 | 最新视频-x88av | 亚洲一区二区三区在线视频 | 亚洲欧美国产日产综合不卡 | 国产成人综合激情视频在线观看 | 精品无码国产自产在线观看水浒传 | 曰韩a级片 | 无码av一区在线观看免费 | 久久婷婷五月综合色首页 | 国产亚洲精品久久久999密壂 |