97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
视频福利一区,亚洲欧洲在线观看视频,黄色调教视频
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-Activin Receptor Type IIB/Cy3 Conjugated antibody (bs-12417R-Cy3)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-12417R-Cy3
英文名稱 Rabbit Anti-Activin Receptor Type IIB/Cy3 Conjugated antibody
中文名稱 Cy3標記的激活素受體2B抗體
別    名 Activin Receptor Type IIB; ACTR-IIB; Activin A receptor type IIB; Activin receptor type 2B; Activin receptor type IIB; Activin receptor type-2B; ActR IIB; ACTR-IIB; ActRIIB; ACVR 2B; ACVR2B; AVR2B_HUMAN; HTX4; MGC116908.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  信號轉導  干細胞  生長因子和激素  激酶和磷酸酶  細胞表面分子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Sheep, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 56kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ACVR2B/ACTR-IIB
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Members of the transforming growth factor b superfamily bind to a pair of transmembrane proteins, known as receptor types I and II, which contain serine/threonine kinases and associate to form a signaling complex (1). Activin has been shown to bind a heteromeric noncovalent complex, which consists of a type I receptor, ACTR-IA (also designated ACVRI and ALK-2) or ACTR-IB (also designated ALK-4 and SKR2), and a type II receptor, ACTR-IIA (also designated ACVR2A) or ACTR-IIB (also designated ACVR2B) (1-6). Both receptor types are highly expressed in brain (5). The activin receptor family members are thought to mediate distinct effects on gene expression, cell differentiation, and morpho- genesis in a dose dependent fashion (5,6).

Function:
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A.

Subunit:
Forms an activin receptor complex with activin type II receptors such as ACVR1B. Interacts with VPS39.

Subcellular Location:
Cell membrane; Single-pass type I membrane protein.

Post-translational modifications:
Phosphorylated. Constitutive phosphorylation is in part catalyzed by its own kinase activity.

DISEASE:
Defects in ACVR2B are the cause of visceral heterotaxy autosomal type 4 (HTX4) [MIM:613751]. A form of visceral heterotaxy, a complex disorder due to disruption of the normal left-right asymmetry of the thoracoabdominal organs. It results in an abnormal arrangement of visceral organs, and a wide variety of congenital defects. Clinical features of visceral heterotaxy type 4 include dextrocardia, right aortic arch and a right-sided spleen, anomalies of the inferior and the superior vena cava, atrial ventricular canal defect with dextro-transposed great arteries, pulmonary stenosis, polysplenia and midline liver.

Similarity:
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.
TGFB receptor subfamily.
Contains 1 protein kinase domain.

Database links:

Entrez Gene: 93 Human

Entrez Gene: 11481 Mouse

Entrez Gene: 25366 Rat

Omim: 602730 Human

SwissProt: Q13705 Human

SwissProt: P27040 Mouse

SwissProt: P38445 Rat

Unigene: 174273 Human

Unigene: 390239 Mouse

Unigene: 24240 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 农田丰满艳肉妇hd | 人妻无码中文字幕永久在线 | 精品久久中文字幕97 | 四虎影院2024 | 亚洲熟女AV综合网五月 | 色视频在线观看免费视频 | 成人免费观看在线 | 亚洲综合在线另类色区奇米 | 少妇穿牛仔裤一级av毛片 | 久久久久人妻一区精品 | 91免费| 久久国产激情视频 | 最好看的中文字幕第一页在线 | 九九欧美视频 | 日本孕妇潮喷高潮视频 | 亚洲国产精品视频一区二区 | 第一次进丫头身体 | 国产成人精品免费视频大 | 男人放进女人阳道动态图 | 国产精品无码dvd在线观看 | 精品国产子伦久久久久久小说 | 亚洲视频一二区 | 黄色录像a级片 | 亚洲AⅤ无码精品色情午在线 | 激情综合色综合啪啪五月丁香搜索 | 91精品国产福利 | 国内自拍片 | 国产手机在线αⅴ片无码观看 | 久久在现视频 | 亚洲乱码中文字幕小综合 | 善良的表妹hd高清中文 | 在线视频观看国产 | 午夜一二区 | 狠狠躁日日躁狂躁夜夜躁 | 免费高清特级毛片A片 | 热久久综合网 | 亚洲狠狠婷婷综合久久久久图片 | av爽爽 | 日韩人妻无码精品专区综合网 | 成熟少妇XXXXX高清视频 | 午夜羞羞影院免费播放在线观看 |