97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
囯产黄色视频一级黄片,麻豆麻豆,动漫羞免费网站中国字幕
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-FRAT1/APC Conjugated antibody (bs-12434R-APC)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-12434R-APC
英文名稱 Rabbit Anti-FRAT1/APC Conjugated antibody
中文名稱 APC標記的原癌基因FRAT1抗體
別    名 FRAT 1; frequently rearranged in advanced T cell lymphomas; Frequently rearranged in advanced T-cell lymphomas; GSK 3 binding protein FRAT1; proto oncogene FRAT1; FRAT1_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  發育生物學  信號轉導  干細胞  淋巴細胞  t-淋巴細胞  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Cow, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 29kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FRAT1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈.
產品介紹 background:
FRAT1 and FRAT2 were originally characterized as proteins frequently rearranged in advanced T cell lymphoma, and they have since been identified as proto-oncogenes involved in tumorigenesis. These proteins share significant homology with the Xenopus glycogen synthase kinase-3 (xGSK-3) binding protein, which is designated GBP and is essential for the formation of the dorsal-ventral axis during embryonic development. Establishment of these embryonic axes is mediated by the Wnt intracellular signaling pathway. Wnt signaling is regulated in part by the activity of GSK-3, which phosphorylates and thereby facilitates the degradation of ?catenin. GBP binds to GSK-3 and inhibits this phosphorylation, resulting in the accumulation of ?catenin and the subsequent transcription of Wnt target genes. Like GBP, FRAT2 has been shown to bind xGSK-3, suggesting that FRAT1 and FRAT2 may be GSK-3 regulatory proteins.

Function:
The protein encoded by the FRAT1 gene belongs to the GSK-3-binding protein family. The protein inhibits GSK-3-mediated phosphorylation of beta-catenin and also positively regulates the Wnt signaling pathway. It may play a role in tumor progression and in lymphomagenesis.

Subunit:
Binds DVL1. Binds GSK-3 and prevent GSK-3-dependent phosphorylation.

Subcellular Location:
Cytoplasmic.

Post-translational modifications:
Phosphorylated (By similarity).

Similarity:
Belongs to the GSK-3-binding protein family.

Database links:
UniProtKB/Swiss-Prot: Q92837.3

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 91麻豆免费观看 | 午夜影院在线午夜影院在线观看 | 一级做a爰片性色毛片是免费 | 久久精品人人爽人人爽 | 欧美jizzhd精品欧美 | 动漫精品视频一区二区三区 | 精品国产伦一区二区三区 | 天天色综| 影音先锋色AV男人资源网 | 中国性感美女一级黄色影片 | 久久水蜜桃亚洲AV无码精品 | 四虎影视在线观看2413 | 高清视频在线观看免费播放 | 欧美黄色一级片视频 | 午夜无码乱码在线观看 | 无码人妻精品一区二区三 | 国产精品亚洲а∨天堂免 | 色综合久久天天综合网 | 日日嗨av一区二区三区四区 | 中文字幕高清av | 久久99热狠狠色一区二区 | 特黄一级 | 国产av一级毛片 | 玖玖精品国产 | 日韩激情无码一级毛片 | 免费一区区三区四区 | 国产人妻高清国产拍精品 | 国产欧美一区二区三区免费 | 国产精品久久久久9999 | 免费视频xxx| 18禁成年免费无码国产 | 91久久丝袜国产露脸动漫 | 91社区在线观看 | 国产精品探花在线观看 | 精品一区二区三区四区 | 中日黄色一级片 | 日产日韩亚洲欧美综合 | 灰色果实哪里黄 | 欧美日韩一区二区精品 | 蜜臀人妻精品一区二区免费 | 97免费超碰 |