97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
日韩一级中文字幕,日韩黄色网络,国产精品视频第一区二区三区
Rabbit Anti-FRAT1/BF350 Conjugated antibody (bs-12434R-BF350)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-12434R-BF350
英文名稱 Rabbit Anti-FRAT1/BF350 Conjugated antibody
中文名稱 BF350標(biāo)記的原癌基因FRAT1抗體
別    名 FRAT 1; frequently rearranged in advanced T cell lymphomas; Frequently rearranged in advanced T-cell lymphomas; GSK 3 binding protein FRAT1; proto oncogene FRAT1; FRAT1_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 腫瘤  細(xì)胞生物  發(fā)育生物學(xué)  信號轉(zhuǎn)導(dǎo)  干細(xì)胞  淋巴細(xì)胞  t-淋巴細(xì)胞  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Cow, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 29kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FRAT1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈.
產(chǎn)品介紹 background:
FRAT1 and FRAT2 were originally characterized as proteins frequently rearranged in advanced T cell lymphoma, and they have since been identified as proto-oncogenes involved in tumorigenesis. These proteins share significant homology with the Xenopus glycogen synthase kinase-3 (xGSK-3) binding protein, which is designated GBP and is essential for the formation of the dorsal-ventral axis during embryonic development. Establishment of these embryonic axes is mediated by the Wnt intracellular signaling pathway. Wnt signaling is regulated in part by the activity of GSK-3, which phosphorylates and thereby facilitates the degradation of ?catenin. GBP binds to GSK-3 and inhibits this phosphorylation, resulting in the accumulation of ?catenin and the subsequent transcription of Wnt target genes. Like GBP, FRAT2 has been shown to bind xGSK-3, suggesting that FRAT1 and FRAT2 may be GSK-3 regulatory proteins.

Function:
The protein encoded by the FRAT1 gene belongs to the GSK-3-binding protein family. The protein inhibits GSK-3-mediated phosphorylation of beta-catenin and also positively regulates the Wnt signaling pathway. It may play a role in tumor progression and in lymphomagenesis.

Subunit:
Binds DVL1. Binds GSK-3 and prevent GSK-3-dependent phosphorylation.

Subcellular Location:
Cytoplasmic.

Post-translational modifications:
Phosphorylated (By similarity).

Similarity:
Belongs to the GSK-3-binding protein family.

Database links:
UniProtKB/Swiss-Prot: Q92837.3

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.kastlife.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
主站蜘蛛池模板: 激情综合婷婷色五月蜜桃 | 一级片免费在线看 | 天天操天天做 | 区区久久久狼 | 中文字幕日韩网站免费视频 | 正在播放国产对白孕妇作爱 | 免费观看的av网站 | 成人国产精品色哟哟 | 好男人好资源在线观看免费视频 | 国产精品久久久久久久久久了 | 国产女教师高潮叫床视频网站 | 亚洲一区二区三区免费观看 | 久久久久国产一级毛片 | 国产精品第一页爽爽影院 | 色呦呦官网 | 玖玖精品在线视频 | 欧美jizzhd精品欧美 | 久久私拍视频 | 台湾毛片 | 亚洲人成精品久久久久 | 666av视频导航 | 亚洲V国产V天堂A无码二区 | 美女视频三区 | 日韩免费成人 | 色综合精品久久久久久久 | 青青草91久久久久久久久 | 久久综合久久综合九色 | 免费黄色网址在线观看 | 少妇被爽到高潮动态图 | 暖暖视频在线观看免费 | 久久精品网址 | 国产亚洲综合精品 | 伊人精品在线观看 | 精品综合久久久久久98 | 强辱丰满人妻hd中文字幕 | 免费人成视频网站在线18 | 人妻无码AV一区二区三区精品 | 中文字幕在线伊人 | 年轻富婆私密推油到高潮 | 欧美男女爱爱视频 | 91伊人|