97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
a毛片视频,日韩欧美一级,高潮又爽又黄又无遮挡免费
Rabbit Anti-Junctophilin-2/Cy7 Conjugated antibody (bs-0702R-Cy7)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說(shuō) 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-0702R-Cy7
英文名稱 Rabbit Anti-Junctophilin-2/Cy7 Conjugated antibody
中文名稱 Cy7標(biāo)記的親聯(lián)蛋白2抗體
別    名 FLJ40969; JP-2; JP2; JPH2; JPH2_HUMAN; Junctophilin 2; Junctophilin type 2; Junctophilin-2; OTTHUMP00000031651; OTTHUMP00000031652.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書 100ul  
研究領(lǐng)域 心血管  細(xì)胞膜蛋白  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Cow, Rabbit, )
產(chǎn)品應(yīng)用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 74kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Junctophilin-2
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. The protein encoded by this gene is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. This gene is a member of the junctophilin gene family. Alternative splicing has been observed at this locus and two variants encoding distinct isoforms are described. [provided by RefSeq, Jul 2008].

Function:
Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. JPH2 is necessary for proper intracellular Ca(2+) signaling in cardiac myocytes via its involvement in ryanodine receptor-mediated calcium ion release. Contributes to the construction of skeletal muscle triad junctions.

Subcellular Location:
Cell membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Single-pass type IV membrane protein. Sarcoplasmic reticulum membrane; Single-pass type IV membrane protein. Note=Localized predominantly on the plasma membrane. The transmembrane domain is anchored in endoplasmic/sarcoplasmic reticulum membrane, while the N-terminal part associates with the plasma membrane. In heart cells, it predominantly associates along Z lines within myocytes. In skeletal muscle, it is specifically localized at the junction of A and I bands.

Tissue Specificity:
Specifically expressed in skeletal muscle and heart.

Post-translational modifications:
Phosphorylation on Ser-165, probably by PKC, affects RYR1-mediated calcium ion release, interaction with TRPC3, and skeletal muscle myotubule development.

DISEASE:
Defects in JPH2 are the cause of familial hypertrophic cardiomyopathy type 17 (CMH17) [MIM:613873]. CMH17 is a hereditary heart disorder characterized by ventricular hypertrophy, which is usually asymmetric and often involves the interventricular septum. The symptoms include dyspnea, syncope, collapse, palpitations, and chest pain. They can be readily provoked by exercise. The disorder has inter- and intrafamilial variability ranging from benign to malignant forms with high risk of cardiac failure and sudden cardiac death.

Similarity:
Belongs to the junctophilin family.
Contains 8 MORN repeats.

Database links:

Entrez Gene: 57158 Human

Entrez Gene: 59091 Mouse

Entrez Gene: 296345 Rat

Omim: 605267 Human

SwissProt: Q9BR39 Human

SwissProt: Q9ET78 Mouse

SwissProt: Q2PS20 Rat

Unigene: 441737 Human

Unigene: 34459 Mouse

Unigene: 6206 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.kastlife.cn 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
主站蜘蛛池模板: 卡一卡二卡三免费视频 | 灰色果实哪里黄 | 18禁无遮挡免费视频网站 | 国产高清无码黄片亚洲大尺度视频 | 久色88 | 一区91| 国产在线观看不卡一区二区三区 | 免费在线观看日韩视频 | 麻豆成人免费视频 | 女人被做到高潮免费视频 | 西西人体午夜大胆无码视频 | 国内毛片毛片毛片毛片毛片 | 免费观看一区二区三区毛片 | 亚洲精品在线观看免费 | 久久999精品久久久有什么优势 | 亚洲V国产V天堂A无码二区 | 国产极品白嫩精品 | 中日韩亚洲人成无码网站 | 欧美精产国品一二三产品区别在哪 | 日韩精品在线免费视频 | 99手机国产精品 | 四虎成人免费视频在线播放 | 亚洲国产成人精品女人久久久久 | 亚洲午夜精品一区二区三区 | 国产裸拍裸体视频在线观看 | 久久久久久久久一区 | www.久久 | 日本精品成人一区二区三区视频 | 国产精品99久久久久久小说 | 无码专区天天躁天天躁在线 | 成人黄色片在线观看 | 日韩免费视频播放 | 青青青国产在线观看免费 | av一区在线 | 特级黄色小视频 | 午夜精品射精入后重之免费观看 | 亚洲成a人片777777久久 | 无码免费一区二区三区免费播放 | 国产成人自拍视频在线 | 一级淫片aaa | 狠狠色狠狠色很很综合很久久 |