97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
a毛片视频,日韩欧美一级,高潮又爽又黄又无遮挡免费
Rabbit Anti-Junctophilin-2/Cy7 Conjugated antibody (bs-0702R-Cy7)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說(shuō) 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-0702R-Cy7
英文名稱 Rabbit Anti-Junctophilin-2/Cy7 Conjugated antibody
中文名稱 Cy7標(biāo)記的親聯(lián)蛋白2抗體
別    名 FLJ40969; JP-2; JP2; JPH2; JPH2_HUMAN; Junctophilin 2; Junctophilin type 2; Junctophilin-2; OTTHUMP00000031651; OTTHUMP00000031652.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書 100ul  
研究領(lǐng)域 心血管  細(xì)胞膜蛋白  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Cow, Rabbit, )
產(chǎn)品應(yīng)用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 74kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Junctophilin-2
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. The protein encoded by this gene is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. This gene is a member of the junctophilin gene family. Alternative splicing has been observed at this locus and two variants encoding distinct isoforms are described. [provided by RefSeq, Jul 2008].

Function:
Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. JPH2 is necessary for proper intracellular Ca(2+) signaling in cardiac myocytes via its involvement in ryanodine receptor-mediated calcium ion release. Contributes to the construction of skeletal muscle triad junctions.

Subcellular Location:
Cell membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Single-pass type IV membrane protein. Sarcoplasmic reticulum membrane; Single-pass type IV membrane protein. Note=Localized predominantly on the plasma membrane. The transmembrane domain is anchored in endoplasmic/sarcoplasmic reticulum membrane, while the N-terminal part associates with the plasma membrane. In heart cells, it predominantly associates along Z lines within myocytes. In skeletal muscle, it is specifically localized at the junction of A and I bands.

Tissue Specificity:
Specifically expressed in skeletal muscle and heart.

Post-translational modifications:
Phosphorylation on Ser-165, probably by PKC, affects RYR1-mediated calcium ion release, interaction with TRPC3, and skeletal muscle myotubule development.

DISEASE:
Defects in JPH2 are the cause of familial hypertrophic cardiomyopathy type 17 (CMH17) [MIM:613873]. CMH17 is a hereditary heart disorder characterized by ventricular hypertrophy, which is usually asymmetric and often involves the interventricular septum. The symptoms include dyspnea, syncope, collapse, palpitations, and chest pain. They can be readily provoked by exercise. The disorder has inter- and intrafamilial variability ranging from benign to malignant forms with high risk of cardiac failure and sudden cardiac death.

Similarity:
Belongs to the junctophilin family.
Contains 8 MORN repeats.

Database links:

Entrez Gene: 57158 Human

Entrez Gene: 59091 Mouse

Entrez Gene: 296345 Rat

Omim: 605267 Human

SwissProt: Q9BR39 Human

SwissProt: Q9ET78 Mouse

SwissProt: Q2PS20 Rat

Unigene: 441737 Human

Unigene: 34459 Mouse

Unigene: 6206 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.kastlife.cn 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
主站蜘蛛池模板: 夜夜躁很很躁日日躁2020 | 久久久久久无码AV成人影院 | 亚洲国产精品成人女人久久久 | 国产AV无码精品国产精品 | a级一级毛片 | 天天躁日日躁aaaa视频 | 男人操女人在线视频 | 国产剧情无码播放在线观看 | WWW.亚洲最大夜色伊人 | 国产精品一区一区三区 | 久久久人精午夜精国 | 久久久久av综合网成人 | 国产精品无码在线 | 国产一级片不卡 | 国产精品一区二区av日韩在线 | 爽妇网国产精品 | 最近免费中文字幕中文高清 | 久久久久久亚洲 | 狠狠躁夜夜躁人人爽蜜桃 | 欧美一区1区三区3区公司 | 欧美色香蕉 | 亚洲中文字幕久久精品无码va | 东北农村女人乱淫免费视频 | 久久玖玖| 国产午夜精品在线 | 亚洲国产良家在线观看 | av私库在线| 国产精品高清视亚洲乱码 | 老司机带带我免费视频 | 免费A级毛片AV无码 爱情岛论坛自拍亚洲品质极速福利 | 色香蕉在线| 人妻夫の上司犯感との中文字幕 | 成人av在线大片 | 成人综合色站 | 国语憿情少妇无码AV | 国产精品久久久久9999爆乳 | 亚洲日韩色在线影院性色 | 在线免费看黄视频 | 久久午夜激情视频 | 狼人青草久久网伊人 | 亚洲第一福利在线观看 |