97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
日韩精品欧美视频,国产色毛片,在线视频成人永久免费
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-Junctophilin-2/PE-Cy5 Conjugated antibody (bs-0702R-PE-Cy5)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-0702R-PE-Cy5
英文名稱 Rabbit Anti-Junctophilin-2/PE-Cy5 Conjugated antibody
中文名稱 PE-Cy5標記的親聯蛋白2抗體
別    名 FLJ40969; JP-2; JP2; JPH2; JPH2_HUMAN; Junctophilin 2; Junctophilin type 2; Junctophilin-2; OTTHUMP00000031651; OTTHUMP00000031652.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 心血管  細胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Cow, Rabbit, )
產品應用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 74kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Junctophilin-2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. The protein encoded by this gene is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. This gene is a member of the junctophilin gene family. Alternative splicing has been observed at this locus and two variants encoding distinct isoforms are described. [provided by RefSeq, Jul 2008].

Function:
Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. JPH2 is necessary for proper intracellular Ca(2+) signaling in cardiac myocytes via its involvement in ryanodine receptor-mediated calcium ion release. Contributes to the construction of skeletal muscle triad junctions.

Subcellular Location:
Cell membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Single-pass type IV membrane protein. Sarcoplasmic reticulum membrane; Single-pass type IV membrane protein. Note=Localized predominantly on the plasma membrane. The transmembrane domain is anchored in endoplasmic/sarcoplasmic reticulum membrane, while the N-terminal part associates with the plasma membrane. In heart cells, it predominantly associates along Z lines within myocytes. In skeletal muscle, it is specifically localized at the junction of A and I bands.

Tissue Specificity:
Specifically expressed in skeletal muscle and heart.

Post-translational modifications:
Phosphorylation on Ser-165, probably by PKC, affects RYR1-mediated calcium ion release, interaction with TRPC3, and skeletal muscle myotubule development.

DISEASE:
Defects in JPH2 are the cause of familial hypertrophic cardiomyopathy type 17 (CMH17) [MIM:613873]. CMH17 is a hereditary heart disorder characterized by ventricular hypertrophy, which is usually asymmetric and often involves the interventricular septum. The symptoms include dyspnea, syncope, collapse, palpitations, and chest pain. They can be readily provoked by exercise. The disorder has inter- and intrafamilial variability ranging from benign to malignant forms with high risk of cardiac failure and sudden cardiac death.

Similarity:
Belongs to the junctophilin family.
Contains 8 MORN repeats.

Database links:

Entrez Gene: 57158 Human

Entrez Gene: 59091 Mouse

Entrez Gene: 296345 Rat

Omim: 605267 Human

SwissProt: Q9BR39 Human

SwissProt: Q9ET78 Mouse

SwissProt: Q2PS20 Rat

Unigene: 441737 Human

Unigene: 34459 Mouse

Unigene: 6206 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 亚洲天堂中文 | 男女后进式猛烈XX00免费视频 | 久久久国产精品 | 国产在线精品一区二区在线看 | 国产成人久久久精品二区三区 | 男人被口爽还是啪啪爽 | 久久精品女人毛片国产 | 91精品国产综合久久久久久丝袜 | 成人午夜在线播放 | 桃子视频在线观看高清免费视频 | 日韩色综合 | 337P亚洲日本中国大胆69 | 日韩一级淫片 | VA在线看国产免费 | 成人国产亚洲精品A区天堂 欧美四虎影院 | 久久只精品国产 | 污污网站国产精品白丝袜 | 大胆欧美熟妇xxbbwwbw | 无码少妇高潮喷水A片免费 欧美性xxxx视频 | 91麻豆入口| 无码免费一区二区三区免费播放 | 欧美粗大无套gay | 婷婷成人丁香五月综合激情 | 国产九色网站 | 亚洲亚洲人成综合丝袜图片 | 国产女教师一爽a片 | 亚洲国产午夜精品 | 色翁荡熄又大又硬又粗又视频图片 | 真人二十三式性视频(动) | 国产成人AV一区二区三区无码 | 沦为公交两奶头春药高潮迭起 | 新版天堂资源中文www官网 | 18禁黄网站禁片无遮挡观看 | AV无码岛国免费动作片 | 亚洲国产精品久久久久久69 | 男男GV白嫩小受GV在线播放 | 色翁荡熄又大又硬又粗又视频图片 | 成人免费看98影视mp4 | 成人一区二区三区久久精品嫩草 | 91夜夜蜜桃臀一区二区三区 | 91精品一区二区三区综合在线爱 |