97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
色诱av手机版,免费亚洲成人,国产一级毛片在线视频
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-DKK2/Cy7 Conjugated antibody (bs-13005R-Cy7)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-13005R-Cy7
英文名稱 Rabbit Anti-DKK2/Cy7 Conjugated antibody
中文名稱 Cy7標記的Wnt通路抑制因子2抗體
別    名 Dickkopf 2; Dickkopf gene 2; Dickkopf homolog 2; Dickkopf related protein 2; Dickkopf-2; Dickkopf-related protein 2; Dickkopf2; DKK 2; Dkk-2; Dkk2; DKK2_HUMAN; hDkk 2; hDkk-2; hDkk2.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  神經生物學  干細胞  細胞凋亡  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Horse, Rabbit, Sheep, )
產品應用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 25kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DKK2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
The Wnt genes are a group of well conserved, cysteine-rich secreted glycoproteins that are required for numerous develop-mental processes including embryogenesis, asymmetric cell division and central nervous system (CNS) patternins. Wnt association with the seven membrane spanning receptor Frizzled, activates Dishevelled, which downregulates glycogen synthase kinase (GSK) through serine phosphorylation, causing the accumulation of b-Catenin and subsequent regulation of developmentally significant Wnt target genes. The Dickkopf family of secreted inhibitors of Wnt signaling ensures proper morphological development by antagonizing different stages of the Wnt cascade. Dkk-2 (Dickkopf-2) is a 259-amino acid secreted protein that is composed of an N-terminal signal peptide and 2 conserved cysteine-rich domains, which are separated by a 50-55-amino acid linker region.

Function:
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.

Subunit:
Interacts with LRP5 and LRP6 (By similarity).

Subcellular Location:
Secreted.

Tissue Specificity:
Expressed in heart, brain, skeletal muscle and lung.

Post-translational modifications:
May be proteolytically processed by a furin-like protease.

Similarity:
Belongs to the dickkopf family.

Database links:

Entrez Gene: 27123 Human

Entrez Gene: 56811 Mouse

Omim: 605415 Human

SwissProt: Q9UBU2 Human

SwissProt: Q9QYZ8 Mouse

SwissProt: Q9DDA4 Xenopus laevis

Unigene: 211869 Human

Unigene: 103593 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 日本超黄视频 | 爱爱欧美| 亚洲国产成人精品福利在线观看 | 欧美一级片久久 | 日本孕妇潮喷高潮视频 | 啊啊啊射了 | 熟妇的奶头又大又粗视频 | 亚韩精品 | 日韩视频一区尤物少妇偷拍 | 中文字幕永久在线 | 国产欧美一区二区三区免费 | 久久久久久久波多野结衣高潮 | 亚洲AV无码日韩AV无码网站冲 | 国产成人涩涩涩视频在线观看 | 一线天逼逼 | 国产精品视频麻豆 | 男人的天堂在线视频 | 99国产欧美 | 国产一级黄色片免费 | 亚洲成人黄色小说 | 色视频一区 | 人人干日日操 | 男女超爽视频免费播放 | 亚洲精品一区二区另类图片 | 亚洲高清一区二 | 人妻无码AV一区二区三区精品 | 精品视频在线观看一区 | 五月丁香六月激情综合在线视频 | 中文字幕日韩在线 | 久热免费 | 天天做天天爱夜夜爽毛片 | 免费观看又色又爽又黄的校园 | 狠狠躁日日躁狂躁夜夜躁 | 天天干网| 91视频在线免费看 | 久久精品精品 | 91精品国产日韩一区二区三区 | 亚洲麻豆 | 国产一级片播放 | 国产精品综合在线观看 | 欧美97 |