97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
国产精品久久久久久久久福交,色婷婷成人在线,国产三级A在线观看
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-FBXO45/PE-Cy5 Conjugated antibody (bs-13150R-PE-Cy5)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-13150R-PE-Cy5
英文名稱 Rabbit Anti-FBXO45/PE-Cy5 Conjugated antibody
中文名稱 PE-Cy5標記的F-box蛋白45抗體
別    名 F box protein 45; F-box only protein 45; F-box/SPRY domain-containing protein 1; FBSP1_HUMAN; FBX45; fbxo45; hFbxo45.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  發育生物學  信號轉導  轉錄調節因子  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Dog, Horse, Rabbit, Sheep, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 31kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FBXO45
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Belonging to the F-box family of proteins, FBXO45 is a 286 amino acid protein that contains one C-terminal F-box domain. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein)-type E3 ubiquitin ligase complex and are involved in substrate recognition and protein recruitment for ubiquitination. They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular mechanisms, including the cell cycle, the immune response, signaling cascades and developmental processes. They function by targeting proteins, such as cyclins, cyclin-dependent kinase inhibitors, I˚B-å and ∫-catenin, for degradation by the proteasome after ubiquitination. Via its F-box domain, FBXO45 can directly interact with Skp1 p19 and CUL-1. FBXO45 has been shown to be an estrogen-induced gene.

Function:
Component of E3 ubiquitin ligase complexes. Required for normal neuromuscular synaptogenesis, axon pathfinding and neuronal migration (By similarity). Plays a role in the regulation of neurotransmission at mature neurons (By similarity). May controls synaptic activity by controlling UNC13A via ubiquitin dependent pathway (By similarity). Specifically recognizes TP73, promoting its ubiquitination and degradation.

Subunit:
Forms a complex with MYCBP2 and SKP1 but does not appear to form an authentic SCF (SKP1-CUL1-F-box protein) complex (By similarity). Interacts (via B30.2/SPRY domain) with TP73 (via SAM domain); leading to TP73 ubiquitination and degradation by proteasome. Interacts (via SRY domain) with UNC13A; leading to degradation of UNC13A by the proteasome (By similarity).

Subcellular Location:
Cell junction > synapse > postsynaptic cell membrane. Cell junction > synapse > presynaptic cell membrane.

Similarity:
Belongs to the FBXO45/Fsn family.
Contains 1 B30.2/SPRY domain.
Contains 1 F-box domain.

Database links:

Entrez Gene: 200933 Human

Entrez Gene: 268882 Mouse

Omim: 609112 Human

SwissProt: P0C2W1 Human

SwissProt: Q8K3B1 Mouse

SwissProt: P0CH38 Rat

Unigene: 169815 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 欧美日韩国产综合视频 | 玖玖精品在线视频 | 丁香五月欧美成人 | 青娱乐久草 | 亚州av久久精品美女模特图片 | 91毛片视频 | 精品综合久久久久久98 | 久久精品国产乱子伦 | 一级黄a视频 | 日本色中色| 色综合久久天天综合网 | 邻居少妇张开腿让我爽了在线观看 | 国产亚洲91 | 亚洲欧美一级夜夜爽 | 久久不卡一区 | 国产视频久久网 | 亚洲理论中文字幕 | 免费黄网站欧美 | 免费黄色视屏 | 激性欧美激情在线 | 两女女百合互慰AV赤裸无遮挡 | 亚洲Aⅴ天堂Av天堂无码麻豆 | 亚洲精品国产精品乱码不卞 | 国产免费拔擦拔擦8x高清在线人 | 国产超a级动作大片中文字幕 | 人人爽在线视频 | 最新视频-x88av | 欧美人与动性xxxxx交性 | 国产精品一区一区三区 | 欧洲免费无线码在线一区 | 亚洲精品乱码久久久久 | 国产精品亚洲一区二区麻豆 | 国产精品高潮呻吟av久久动 | 46集连续剧免费观看 | 蜜臀久久精品久久久久久酒店? | 九九在线中文字幕无码 | 99精品成人无码A片观看 | 国产日韩视频在线播放 | 精品久久综合1区2区3区激情 | 久久99视频精品 | 无码专区男人本色 |