97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
337p日本大胆欧美人,日韩av在线播放观看,黄色在线视频网站
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-GPR37/PE-Cy7 Conjugated antibody (bs-13534R-PE-Cy7)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-13534R-PE-Cy7
英文名稱 Rabbit Anti-GPR37/PE-Cy7 Conjugated antibody
中文名稱 PE-Cy7標記的G蛋白偶聯受體37/帕金森相關內皮素受體樣受體抗體
別    名 GPCR GPR37; EDNRBL; Endothelin B receptor like protein 1; Endothelin B receptor-like protein 1; Endothelin receptor type B like; ETBR LP 1; ETBR-LP-1; ETBRLP1; G protein coupled receptor 37; G protein coupled receptor 37 endothelin receptor type B like; Gpr37; GPR37_HUMAN; hET(B)R LP; hET(B)RLP; PAELR; Parkin associated endothelin receptor like receptor; Parkin-associated endothelin receptor-like receptor; Probable G protein coupled receptor 37; Probable G-protein coupled receptor 37; GPCR 37.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  神經生物學  信號轉導  G蛋白偶聯受體  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Rabbit, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 67kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GPR37
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Pael receptor (Pael-R), also known as Parkin-associated endothelin receptor-like receptor, is a putative G protein-coupled transmembrane polypeptide. The gene that encodes Pael-R maps to chromosome 7q31. Pael-R belongs to family 1 of the G protein-coupled receptors and is mainly expressed in the brain. Pael-R interacts with Parkin, the gene product responsible for familial Parkinson’s disease.

Function:
Orphan receptor. May have a unique functional role in the central nervous system.

Subunit:
Forms a complex with PARK2, STUB1 and HSP70. The amount of STUB1 in the complex increases during ER stress. STUB1 promotes the dissociation of HSP70 from PARK2, thus facilitating PARK2-mediated GPR37 ubiquitination. Interacts with PACRG.

Subcellular Location:
Cell membrane. Endoplasmic reticulum membrane.

Tissue Specificity:
Expressed in brain and spinal cord, and at lower levels in testis, placenta and liver, but no detectable expression observed in any other tissue. When overexpressed in cells, tends to become insoluble and unfolded. Accumulation of the unfolded protein may lead to dopaminergic neuronal death in juvenile Parkinson disease (PDJ).

Post-translational modifications:
Ubiquitinated by PARK2 in the presence of UBE2E1 and UBE2L3 in the endoplasmic reticulum. The unfolded form is specifically ubiquitinated by SYVN1, which promotes its proteasomal degradation and prevents neuronal cell death.

DISEASE:
Expressed in brain and spinal cord, and at lower levels in testis, placenta and liver, but no detectable expression observed in any other tissue. When overexpressed in cells, tends to become insoluble and unfolded. Accumulation of the unfolded protein may lead to dopaminergic neuronal death in juvenile Parkinson disease (PDJ).

Similarity:
Belongs to the G-protein coupled receptor 1 family.

Database links:

Entrez Gene: 2861 Human

Entrez Gene: 14763 Mouse

Entrez Gene: 117549 Rat

Omim: 602583 Human

SwissProt: O15354 Human

SwissProt: Q9QY42 Mouse

SwissProt: Q9QYC6 Rat

Unigene: 731392 Human

Unigene: 409670 Mouse

Unigene: 28035 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 久久久久久国产精品免费无遮挡 | 亚洲HEYZO专区无码综合 | 在线免费观看日本视频 | h无码精品动漫尤物 | 麻豆精品区 | 国产老女人乱淫免费 | 国语一级片 | 青青草综合在线 | 黄色一区二区在线 | 免费无码成人AV片在线在线播放 | 色97色成人 | 午夜影院免费视频 | 国产一区二区成人久久免费影院 | 成人午夜片av在线看 | 日本www免费视频网站在线观看 | AV人摸人人人澡人人超碰手机版 | 真人在线观看色网视频 | 蜜臀av免费一区二区三区久久乐 | 亚洲国产精品一区二区第一页 | 天地争霸美猴王国语在线观看免费 | 国产高清www午色夜 国产精品yjizz视频网 | 一级片免费在线看 | 日韩精品一区二区三区中文无码 | 18禁美女裸体爆乳无遮挡 | 国产亚洲精品第一综合不卡 | 国产精品一区二区三区视频网站 | 国产内射老熟女aaaa | 黄色毛片一级视频 | 亚洲破处av| 日韩久久无码免费看A | 岛国激情av| 中日黄色一级片 | 乱人伦人妻中文字幕无码久久网 | 夜夜躁狠狠躁日日躁视频 | 亚洲爆乳少妇无码激情 | 国产在线精品拍揄自揄免费 | 日日躁夜夜躁人人揉av五月天 | 91sex国产海角社区 | 亚洲成人免费视频在线 | 92国产精品偷窥熟女精品视频 | 三级无码AV在线观看网址 |