97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
日日橹狠狠爱欧美超碰,99爱精品,嫩草在线观看
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-GPR40/Gold Conjugated antibody (bs-13535R-Gold)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產品編號 bs-13535R-Gold
英文名稱 Rabbit Anti-GPR40/Gold Conjugated antibody
中文名稱 膠體金標記的G蛋白偶聯受體40抗體
別    名 GPCR GPR40; FFA1R; FFAR 1; FFAR1; FFAR1_HUMAN; Free fatty acid receptor 1; G protein coupled receptor 40; G-protein coupled receptor 40; GPR 40; GPCR 40.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 腫瘤  細胞生物  信號轉導  糖尿病  G蛋白偶聯受體  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human,  (predicted: Mouse, Rat, Dog, Pig, )
產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 32kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GPR40
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產品介紹 background:
G protein coupled receptors provide attractive targets for drug therapy due to the sheer size and diversity of ligands within this receptor family. G protein-coupled receptor 40 (GPR40) functions as a cell-surface receptor for long-chain free fatty acids (FFAs). FFAs provide an important energy source, but also function as signaling molecules in various pathways, notably the process of insulin secretion. In pancreatic tissue, the interaction of long chain FFAs with GPR40 amplifies glucose-stimulated insulin secretion from beta cells, suggesting a possible role for GPR40 in the treatment of diabetes associated with insulin-deficiency. Specifically, the Arg211His polymorphism in the GPR40 gene may contribute to the variation of insulin secretory capacity in Japanese men. Also, GPR40 may be involved in the control of breast cancer cell growth by fatty acids and, therefore, provide a link between fat and cancer.

Function:
Receptor for medium and long chain saturated and unsaturated fatty acids. Binding of the ligand increase intracellular calcium concentration and amplify glucose-stimulated insulin secretion. The activity of this receptor is mediated by G-proteins that activate phospholipase C. Seems to act through a G(q) and G(i)-mediated pathway.

Subcellular Location:
Cell membrane.

Tissue Specificity:
Expressed abundantly in pancreatic beta cells.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

Database links:

Entrez Gene: 2864 Human

Entrez Gene: 233081 Mouse

Entrez Gene: 266607 Rat

Omim: 603820 Human

SwissProt: O14842 Human

SwissProt: Q76JU9 Mouse

SwissProt: Q8K3T4 Rat

Unigene: 248127 Human

Unigene: 425422 Mouse

Unigene: 86438 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 国产精品毛片va一区二区 | 裸男网站gv | 欧美日韩在线影院 | 国产剧情乱偷 | 影院一区二区 | 国产成人AV性色在线影院色戒 | 毛片av一区二区 | 日韩精品一区二区三区蜜臀 | 精品久久久久久久久久中文字幕 | 一级色毛片 | 一级做性色a爱片久久毛片欧 | 伊人一区二区三区 | 黄色av| 人妻少妇看A偷人无码精品 在教室伦流澡到高潮h麻豆 | 国产亚洲精品久久久999密壂 | 亚洲日本精品一区 | 双腿被绑成M型调教PLAY照片 | 免费黄网站欧美 | av视屏在线 | 久久99精品国产麻豆婷婷小说 | 成人午夜爽爽爽免费视频 | 久久精品一级爱片 | 亚洲欧洲国产精品久久 | 亚洲av国产国产久青草 | 国产三级欧美三级 | 午夜在线播放视频 | 精品视频免费播放 | 精品少妇的一区二区三区四区 | 99爱视频 | 亚洲中文字幕aⅴ无码天堂 成人黄网视频在线观看 | 少妇精品亚洲一区二区成人 | 大地资源免费更新在线播放 | 中文字幕永久在线播放 | 国产又粗又黄又爽又硬的软件 | 日本69视频 | 日本一卡精品视频免费 | 国产人妻精品无码AV在线 | www480jcom四虎 | 国产精品爽爽久久久久久 | 日本xxxx裸体xxxx野外 | 国产免费久久精品99RE丫丫 |