97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
欧美日韩人妻精品一区二区三区 ,手机av一区,最新se94se在线欧美
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-GPR40/AP Conjugated antibody (bs-13535R-AP)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-13535R-AP
英文名稱 Rabbit Anti-GPR40/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標記的G蛋白偶聯受體40抗體
別    名 GPCR GPR40; FFA1R; FFAR 1; FFAR1; FFAR1_HUMAN; Free fatty acid receptor 1; G protein coupled receptor 40; G-protein coupled receptor 40; GPR 40; GPCR 40.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  信號轉導  糖尿病  G蛋白偶聯受體  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human,  (predicted: Mouse, Rat, Dog, Pig, )
產品應用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 32kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GPR40
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
G protein coupled receptors provide attractive targets for drug therapy due to the sheer size and diversity of ligands within this receptor family. G protein-coupled receptor 40 (GPR40) functions as a cell-surface receptor for long-chain free fatty acids (FFAs). FFAs provide an important energy source, but also function as signaling molecules in various pathways, notably the process of insulin secretion. In pancreatic tissue, the interaction of long chain FFAs with GPR40 amplifies glucose-stimulated insulin secretion from beta cells, suggesting a possible role for GPR40 in the treatment of diabetes associated with insulin-deficiency. Specifically, the Arg211His polymorphism in the GPR40 gene may contribute to the variation of insulin secretory capacity in Japanese men. Also, GPR40 may be involved in the control of breast cancer cell growth by fatty acids and, therefore, provide a link between fat and cancer.

Function:
Receptor for medium and long chain saturated and unsaturated fatty acids. Binding of the ligand increase intracellular calcium concentration and amplify glucose-stimulated insulin secretion. The activity of this receptor is mediated by G-proteins that activate phospholipase C. Seems to act through a G(q) and G(i)-mediated pathway.

Subcellular Location:
Cell membrane.

Tissue Specificity:
Expressed abundantly in pancreatic beta cells.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

Database links:

Entrez Gene: 2864 Human

Entrez Gene: 233081 Mouse

Entrez Gene: 266607 Rat

Omim: 603820 Human

SwissProt: O14842 Human

SwissProt: Q76JU9 Mouse

SwissProt: Q8K3T4 Rat

Unigene: 248127 Human

Unigene: 425422 Mouse

Unigene: 86438 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 久久精品女人毛片国产 | 亚洲精品无码国产 | 斗罗大陆4终极斗罗免费观看 | 影音先锋亚洲熟女av网 | 91视频专区| 91精品一区二区三区在线观看 | 亚洲色无码中文字幕手机在线 | 无遮无挡爽爽免费视频 | 国产一区二区视频免费 | 国产精品96久久久久久又黄又硬 | 乱60一70归性欧老妇 | 特级毛片www欧美 | 欧美亚洲日韩国产网站 | 热久久性 | 91九色国产ts另类人妖 | 久久性生活片 | 久久免费的精品国产v∧ | 91日韩精品视频 | 亚洲性AV网站 | 农田丰满艳肉妇hd | 国产高清福利无码视频 | 久久久久久久久久久久久久久国产 | 欧美日韩亚洲中文字幕二区 | 色啪视频| 毛片在线看片 | 亚洲视频免费在线播放 | 无码专区—va亚洲v专区 | 亚洲精品无码久久久久秋霞 | 国产剧情AV麻豆香蕉精品 | 男人扒开女人内裤强吻桶进去 | 国产精品久久久久久免费一级 | 男人的天堂av社区在线 | 亚洲一区三区在线观看 | 国产精品久久久亚洲一区 | a免费在线观看 | 麻豆一区二区大豆行情 | 日韩国产免费一区二区三区 | 爱av在线 | 91亚洲一区二区 | 欧美日本日韩 | 少妇又爽又刺激视频 |