97久久久精品综合88久久_亚洲国产精品一_久热热国产久热_97操操操_北条麻妃在线免费观看_精品国自产拍天天拍

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
午夜精品久久久久久久四虎美女版,91免费看国产,国产揄拍国产精品
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-GPR40/Cy5 Conjugated antibody (bs-13535R-Cy5)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-13535R-Cy5
英文名稱 Rabbit Anti-GPR40/Cy5 Conjugated antibody
中文名稱 Cy5標記的G蛋白偶聯受體40抗體
別    名 GPCR GPR40; FFA1R; FFAR 1; FFAR1; FFAR1_HUMAN; Free fatty acid receptor 1; G protein coupled receptor 40; G-protein coupled receptor 40; GPR 40; GPCR 40.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  信號轉導  糖尿病  G蛋白偶聯受體  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human,  (predicted: Mouse, Rat, Dog, Pig, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 32kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GPR40
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
G protein coupled receptors provide attractive targets for drug therapy due to the sheer size and diversity of ligands within this receptor family. G protein-coupled receptor 40 (GPR40) functions as a cell-surface receptor for long-chain free fatty acids (FFAs). FFAs provide an important energy source, but also function as signaling molecules in various pathways, notably the process of insulin secretion. In pancreatic tissue, the interaction of long chain FFAs with GPR40 amplifies glucose-stimulated insulin secretion from beta cells, suggesting a possible role for GPR40 in the treatment of diabetes associated with insulin-deficiency. Specifically, the Arg211His polymorphism in the GPR40 gene may contribute to the variation of insulin secretory capacity in Japanese men. Also, GPR40 may be involved in the control of breast cancer cell growth by fatty acids and, therefore, provide a link between fat and cancer.

Function:
Receptor for medium and long chain saturated and unsaturated fatty acids. Binding of the ligand increase intracellular calcium concentration and amplify glucose-stimulated insulin secretion. The activity of this receptor is mediated by G-proteins that activate phospholipase C. Seems to act through a G(q) and G(i)-mediated pathway.

Subcellular Location:
Cell membrane.

Tissue Specificity:
Expressed abundantly in pancreatic beta cells.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

Database links:

Entrez Gene: 2864 Human

Entrez Gene: 233081 Mouse

Entrez Gene: 266607 Rat

Omim: 603820 Human

SwissProt: O14842 Human

SwissProt: Q76JU9 Mouse

SwissProt: Q8K3T4 Rat

Unigene: 248127 Human

Unigene: 425422 Mouse

Unigene: 86438 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.kastlife.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 国产精品蜜臀av免费观看四虎 | 色婷婷tv| av资源免费观看 | 国产女教师一爽a片 | 任我爽橹在线视频精品583 | 99久RE热视频这里只有精品6 | 网站黄色在线观看 | 国产鲁鲁视频在线观看 | aaa日本高清在线播放免费观看 | 国产一级黄色片免费 | 91精品久久久久久久久中文字幕 | www日韩高清| 国产精品久久久久9999爆乳 | 欧美性猛交久久久乱大交小说 | 秋霞久久久 | 直接看片的av网址在线看片 | 欧美黑人又粗又大久久久 | 日本男人天堂 | 97成人资源网 | 日韩免费视频播放 | 久久精品国产欧美 | 色噜噜一区二区三区 | 中日黄色一级片 | 欧美日本在线一区 | 日韩中文字幕无码高清毛片 | 国产精品午夜爆乳美女 | 在线无码成本人视频动漫 | 日本黄色一级片免费看 | 欧美黄色性生活视频 | 亚洲人成网站在小说 | 韩日中文字幕 | 开心五月激情综合婷婷 | 国产欧美一区二区三区久久人妖 | 欧美成人免费在线视频 | 国产精品久久一区主播 | 色欧美在线视频 | 日日摸夜夜添夜夜无码区 | 久久精品aⅴ无码中文字字幕 | 日日爱69| 日本在线播放视频 | 鲁大师一区影视 |